Nineteen of 61 Stage I or II mammary-cancer bearers developed conventionally detectable metastases within 8-44 (median 15) months of commencing follow-up. Serum pregnancy-associated macroglobulin (PAM, PAG, O2 PAG) rose by > 75% above baseline values before detection of metastases in all but 4 of these 19 patients and in 11/42 remaining well. The means of the maximum percentage rises in PAM were 286 for the metastatic and 67 for the well patients (P<0-01 in a Mann-Whitney U-test).
|Number of pages||0|
|Journal||British Journal of Cancer|
|Publication status||Published - 1979|
- mammary micrometastases