Comparison of PAM and CEA as detectors of mammary micrometastases

J.M. Anderson, S.K. Jhunjhunwala, J.M. Ewan, W.H. Stimson, G. Gettinby

Research output: Contribution to journalArticlepeer-review


Nineteen of 61 Stage I or II mammary-cancer bearers developed conventionally detectable metastases within 8-44 (median 15) months of commencing follow-up. Serum pregnancy-associated macroglobulin (PAM, PAG, O2 PAG) rose by > 75% above baseline values before detection of metastases in all but 4 of these 19 patients and in 11/42 remaining well. The means of the maximum percentage rises in PAM were 286 for the metastatic and 67 for the well patients (P<0-01 in a Mann-Whitney U-test).
Original languageEnglish
Pages (from-to)320-320
Number of pages0
JournalBritish Journal of Cancer
Issue number2
Publication statusPublished - 1979


  • PAM
  • CEA
  • mammary micrometastases


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