Comparison of PAM and CEA as detectors of mammary micrometastases

J.M. Anderson, S.K. Jhunjhunwala, J.M. Ewan, W.H. Stimson, G. Gettinby

Research output: Contribution to journalArticle

Abstract

Nineteen of 61 Stage I or II mammary-cancer bearers developed conventionally detectable metastases within 8-44 (median 15) months of commencing follow-up. Serum pregnancy-associated macroglobulin (PAM, PAG, O2 PAG) rose by > 75% above baseline values before detection of metastases in all but 4 of these 19 patients and in 11/42 remaining well. The means of the maximum percentage rises in PAM were 286 for the metastatic and 67 for the well patients (P<0-01 in a Mann-Whitney U-test).
Original languageEnglish
Pages (from-to)320-320
Number of pages0
JournalBritish Journal of Cancer
Volume40
Issue number2
Publication statusPublished - 1979

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Neoplasm Micrometastasis
Nonparametric Statistics
Breast
Neoplasm Metastasis
Pregnancy
Serum

Keywords

  • PAM
  • CEA
  • mammary micrometastases

Cite this

Anderson, J. M., Jhunjhunwala, S. K., Ewan, J. M., Stimson, W. H., & Gettinby, G. (1979). Comparison of PAM and CEA as detectors of mammary micrometastases. British Journal of Cancer, 40(2), 320-320.
Anderson, J.M. ; Jhunjhunwala, S.K. ; Ewan, J.M. ; Stimson, W.H. ; Gettinby, G. / Comparison of PAM and CEA as detectors of mammary micrometastases. In: British Journal of Cancer. 1979 ; Vol. 40, No. 2. pp. 320-320.
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Anderson, JM, Jhunjhunwala, SK, Ewan, JM, Stimson, WH & Gettinby, G 1979, 'Comparison of PAM and CEA as detectors of mammary micrometastases', British Journal of Cancer, vol. 40, no. 2, pp. 320-320.

Comparison of PAM and CEA as detectors of mammary micrometastases. / Anderson, J.M.; Jhunjhunwala, S.K.; Ewan, J.M.; Stimson, W.H.; Gettinby, G.

In: British Journal of Cancer, Vol. 40, No. 2, 1979, p. 320-320.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of PAM and CEA as detectors of mammary micrometastases

AU - Anderson, J.M.

AU - Jhunjhunwala, S.K.

AU - Ewan, J.M.

AU - Stimson, W.H.

AU - Gettinby, G.

PY - 1979

Y1 - 1979

N2 - Nineteen of 61 Stage I or II mammary-cancer bearers developed conventionally detectable metastases within 8-44 (median 15) months of commencing follow-up. Serum pregnancy-associated macroglobulin (PAM, PAG, O2 PAG) rose by > 75% above baseline values before detection of metastases in all but 4 of these 19 patients and in 11/42 remaining well. The means of the maximum percentage rises in PAM were 286 for the metastatic and 67 for the well patients (P<0-01 in a Mann-Whitney U-test).

AB - Nineteen of 61 Stage I or II mammary-cancer bearers developed conventionally detectable metastases within 8-44 (median 15) months of commencing follow-up. Serum pregnancy-associated macroglobulin (PAM, PAG, O2 PAG) rose by > 75% above baseline values before detection of metastases in all but 4 of these 19 patients and in 11/42 remaining well. The means of the maximum percentage rises in PAM were 286 for the metastatic and 67 for the well patients (P<0-01 in a Mann-Whitney U-test).

KW - PAM

KW - CEA

KW - mammary micrometastases

UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010021/pdf/brjcancer00142-0118.pdf

M3 - Article

VL - 40

SP - 320

EP - 320

JO - British Journal of Cancer

JF - British Journal of Cancer

SN - 0007-0920

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ER -

Anderson JM, Jhunjhunwala SK, Ewan JM, Stimson WH, Gettinby G. Comparison of PAM and CEA as detectors of mammary micrometastases. British Journal of Cancer. 1979;40(2):320-320.