Comparing placentas from normal and abnormal pregnancies

Alexander Heazell, SL Cotter, L. Gallimore, David Greenhalgh, S. Kennedy, V. Klika, M. Kritz, P. Nelson, Katharine Preedy, I. Pu, A. Stechi, J. Siggers, R. Whittaker

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Abstract

This report describes work carried out at a Mathematics-in-Medicine Study Group. It is believed that placenta shape villous network characteristics are strongly linked to the placenta’s efficiency, and hence to pregnancy outcome. We were asked to consider mathematical ways to describe the shape and other characteristics of a placenta, as well as forming mathematical models for placenta development.
In this report we propose a number of possible measure of placental shape, form, and efficiency, which can be computed from images already obtained. We also consider various models for the early development of placentas and the growth of the villous tree.
Original languageEnglish
Number of pages66
Publication statusPublished - 2010

Publication series

NameUK Mathematics-in-Medicine Study Groups series

Keywords

  • placenta
  • normal pregnancy
  • abnormal pregnancy
  • comparison of placentas
  • macroscopic and microscopic differences
  • data

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    Heazell, A., Cotter, SL., Gallimore, L., Greenhalgh, D., Kennedy, S., Klika, V., Kritz, M., Nelson, P., Preedy, K., Pu, I., Stechi, A., Siggers, J., & Whittaker, R. (2010). Comparing placentas from normal and abnormal pregnancies.