Comparing neutral (monometallic) and anionic (bimetallic) aluminium complexes in hydroboration catalysis: influences of lithium cooperation and ligand set

Victoria A. Pollard; M. Àngeles Fuentes; Alan R. Kennedy; Ross McLellan; Robert E. Mulvey

doi:10.1002/anie.201806168

Comparing neutral (monometallic) and anionic (bimetallic) aluminium complexes in hydroboration catalysis: influences of lithium cooperation and ligand set

Victoria A. Pollard, M. Àngeles Fuentes, Alan R. Kennedy, Ross McLellan, Robert E. Mulvey

Pure And Applied Chemistry

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80 Citations (Scopus)

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Abstract

Bimetallic lithium aluminates and neutral aluminum counterparts are compared as catalysts in hydroboration reactions with aldehydes, ketones, imines and alkynes. Possessing Li–Al cooperativity, ate catalysts are found to be generally superior. Catalytic activity is also influenced by the ligand set, alkyl and/or amido. Devoid of an Al−H bond, iBu2Al(TMP) operates as a masked hydride reducing benzophenone through a β‐Η transfer process. This catalyst library therefore provides an entry point into the future design of Al catalysts targeting substrate specific transformations.

Original language	English
Number of pages	6
Journal	Angewandte Chemie International Edition
Early online date	15 Jun 2018
DOIs	https://doi.org/10.1002/anie.201806168
Publication status	E-pub ahead of print - 15 Jun 2018

Keywords

bimetallic lithium aluminates
neutral aluminium
hydroboration reactions
catalyst activity

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10.1002/anie.201806168Licence: CC BY 4.0

Pollard-etal-ACIE-2018-Comparing-neutral-monometallic-and-anionic-bimetallic-aluminium-complexes-in-hydroboration-catalysisFinal published version, 1.3 MBLicence: CC BY 4.0

Cite this

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title = "Comparing neutral (monometallic) and anionic (bimetallic) aluminium complexes in hydroboration catalysis: influences of lithium cooperation and ligand set",

abstract = "Bimetallic lithium aluminates and neutral aluminum counterparts are compared as catalysts in hydroboration reactions with aldehydes, ketones, imines and alkynes. Possessing Li–Al cooperativity, ate catalysts are found to be generally superior. Catalytic activity is also influenced by the ligand set, alkyl and/or amido. Devoid of an Al−H bond, iBu2Al(TMP) operates as a masked hydride reducing benzophenone through a β‐Η transfer process. This catalyst library therefore provides an entry point into the future design of Al catalysts targeting substrate specific transformations.",

keywords = "bimetallic lithium aluminates, neutral aluminium, hydroboration reactions, catalyst activity",

author = "Pollard, {Victoria A.} and Fuentes, {M. {\`A}ngeles} and Kennedy, {Alan R.} and Ross McLellan and Mulvey, {Robert E.}",

year = "2018",

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doi = "10.1002/anie.201806168",

language = "English",

journal = "Angewandte Chemie International Edition",

issn = "1433-7851",

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TY - JOUR

T1 - Comparing neutral (monometallic) and anionic (bimetallic) aluminium complexes in hydroboration catalysis

T2 - influences of lithium cooperation and ligand set

AU - Pollard, Victoria A.

AU - Fuentes, M. Àngeles

AU - Kennedy, Alan R.

AU - McLellan, Ross

AU - Mulvey, Robert E.

PY - 2018/6/15

Y1 - 2018/6/15

N2 - Bimetallic lithium aluminates and neutral aluminum counterparts are compared as catalysts in hydroboration reactions with aldehydes, ketones, imines and alkynes. Possessing Li–Al cooperativity, ate catalysts are found to be generally superior. Catalytic activity is also influenced by the ligand set, alkyl and/or amido. Devoid of an Al−H bond, iBu2Al(TMP) operates as a masked hydride reducing benzophenone through a β‐Η transfer process. This catalyst library therefore provides an entry point into the future design of Al catalysts targeting substrate specific transformations.

AB - Bimetallic lithium aluminates and neutral aluminum counterparts are compared as catalysts in hydroboration reactions with aldehydes, ketones, imines and alkynes. Possessing Li–Al cooperativity, ate catalysts are found to be generally superior. Catalytic activity is also influenced by the ligand set, alkyl and/or amido. Devoid of an Al−H bond, iBu2Al(TMP) operates as a masked hydride reducing benzophenone through a β‐Η transfer process. This catalyst library therefore provides an entry point into the future design of Al catalysts targeting substrate specific transformations.

KW - bimetallic lithium aluminates

KW - neutral aluminium

KW - hydroboration reactions

KW - catalyst activity

UR - https://onlinelibrary.wiley.com/journal/15213773

U2 - 10.1002/anie.201806168

DO - 10.1002/anie.201806168

M3 - Article

SN - 1433-7851

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

ER -

Comparing neutral (monometallic) and anionic (bimetallic) aluminium complexes in hydroboration catalysis: influences of lithium cooperation and ligand set

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Doctoral Training Partnership (DTP - University of Strathclyde) | Pollard-Nelson, Victoria

Data for: "Comparing neutral (monometallic) and anionic (bimetallic) aluminium complexes in hydroboration catalysis: influences of lithium cooperation and ligand set"

Alkali Metal Mediation in Synthesis and Homogeneous Catalysis

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Comparing neutral (monometallic) and anionic (bimetallic) aluminium complexes in hydroboration catalysis: influences of lithium cooperation and ligand set

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Projects

Doctoral Training Partnership (DTP - University of Strathclyde) | Pollard-Nelson, Victoria

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Data for: "Comparing neutral (monometallic) and anionic (bimetallic) aluminium complexes in hydroboration catalysis: influences of lithium cooperation and ligand set"

Activities

Alkali Metal Mediation in Synthesis and Homogeneous Catalysis

Cite this