Comparative study of the swabbing properties of seven commercially available swab materials for cleaning verification

DK Corrigan, S Piletsky, S McCrossen

Research output: Contribution to journalArticle

Abstract

This article compares the technical performances of several different commercially available swabbing materials for the purpose of cleaning verification. A steel surface was soiled with solutions of acetaminophen, nicotinic acid, diclofenac, and benzamidine and wiped with each swabbing material. The compounds were extracted with water or ethanol (depending on polarity of analyte) and their concentration in extract was quantified spectrophotometrically. The study also investigated swab debris on the wiped surface. The swab performances were compared and the best swab material was identified.
LanguageEnglish
Pages184-193
Number of pages10
JournalPDA Journal of Pharmaceutical Science and Technology
Volume63
Issue number2
Publication statusPublished - 2009

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Diclofenac
Niacin
Steel
Acetaminophen
Ethanol
Water
benzamidine

Cite this

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abstract = "This article compares the technical performances of several different commercially available swabbing materials for the purpose of cleaning verification. A steel surface was soiled with solutions of acetaminophen, nicotinic acid, diclofenac, and benzamidine and wiped with each swabbing material. The compounds were extracted with water or ethanol (depending on polarity of analyte) and their concentration in extract was quantified spectrophotometrically. The study also investigated swab debris on the wiped surface. The swab performances were compared and the best swab material was identified.",
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Comparative study of the swabbing properties of seven commercially available swab materials for cleaning verification. / Corrigan, DK; Piletsky, S; McCrossen, S.

In: PDA Journal of Pharmaceutical Science and Technology, Vol. 63, No. 2, 2009, p. 184-193.

Research output: Contribution to journalArticle

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