TY - CHAP
T1 - Comparative genomics reveals what makes an enterobacterial plant pathogen
AU - Toth, Ian K.
AU - Pritchard, Leighton
AU - Birch, Paul R.J.
PY - 2006/9/8
Y1 - 2006/9/8
N2 - The bacterial family Enterobacteriaceae contains some of the most devastating human and animal pathogens, including Escherichia coli, Salmonella enterica and species of Yersinia and Shigella. These are among the best-studied of any organisms, yet there is much to be learned about the nature and evolution of interactions with their hosts and with the wider environment. Comparative and functional genomics have fundamentally improved our understanding of their modes of adaptation to different ecological niches and the genes that determine their pathogenicity. In addition to animal pathogens, Enterobacteriaceae include important plant pathogens, such as Erwinia carotovora subsp. atroseptica (Eca), the first plant-pathogenic enterobacterium to be sequenced (20). This review focuses on genomic comparisons between Eca and other enterobacteria, with particular emphasis on the differences that exemplify or explain the plant-associated lifestyle(s) of Eca. Horizontal gene transfer in Eca may directly have led to the acquisition of a number of determinants that mediate its interactions, pathogenic or otherwise, with plants, offering a glimpse into its evolutionary divergence from animal-pathogenic ennterobacteria.
AB - The bacterial family Enterobacteriaceae contains some of the most devastating human and animal pathogens, including Escherichia coli, Salmonella enterica and species of Yersinia and Shigella. These are among the best-studied of any organisms, yet there is much to be learned about the nature and evolution of interactions with their hosts and with the wider environment. Comparative and functional genomics have fundamentally improved our understanding of their modes of adaptation to different ecological niches and the genes that determine their pathogenicity. In addition to animal pathogens, Enterobacteriaceae include important plant pathogens, such as Erwinia carotovora subsp. atroseptica (Eca), the first plant-pathogenic enterobacterium to be sequenced (20). This review focuses on genomic comparisons between Eca and other enterobacteria, with particular emphasis on the differences that exemplify or explain the plant-associated lifestyle(s) of Eca. Horizontal gene transfer in Eca may directly have led to the acquisition of a number of determinants that mediate its interactions, pathogenic or otherwise, with plants, offering a glimpse into its evolutionary divergence from animal-pathogenic ennterobacteria.
KW - Erwinia
KW - horizontal gene transfer
KW - phytopathogen
KW - soft rot
KW - type III secretion
KW - plant disease
UR - http://www.scopus.com/inward/record.url?scp=33748959178&partnerID=8YFLogxK
U2 - 10.1146/annurev.phyto.44.070505.143444
DO - 10.1146/annurev.phyto.44.070505.143444
M3 - Chapter
C2 - 16704357
AN - SCOPUS:33748959178
SN - 0824313445
SN - 9780824313449
VL - 44
T3 - Annual Review of Phytopathology
SP - 305
EP - 336
BT - Annual Review of Phytopathology
A2 - Alfen, Dawson
CY - Palo Alto, California
ER -