Combining polymers with the functionality of proteins: new concepts for atom transfer radical polymerization, nanoreactors and damage self-reporting materials

Nico Bruns, Samuel Lörcher, Katarzyna Makyla, Jonas Pollarda, Kasper Renggli, Mariana Spulber

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Proteins are macromolecules with a great diversity of functions. By combining these biomolecules with polymers, exciting opportunities for new concepts in polymer sciences arise. This highlight exemplifies the aforementioned with current research results of our group. We review our discovery that the proteins horseradish peroxidase and hemoglobin possess ATRPase activity, i.e. they catalyze atom transfer radical polymerizations. Moreover, a permeabilization method for polymersomes is presented, where the photoreaction of an α-hydroxyalkylphenone with block copolymer vesicles yields enzyme-containing nanoreactors. A further intriguing possibility to obtain functional nanoreactors is to enclose a polymerization catalyst into the thermosome, a protein cage from the family of chaperonins. Last but not least, fluorescent proteins are discussed as mechanoresponsive molecular sensors that report microdamages within fiber-reinforced composite materials.

Original languageEnglish
Pages (from-to)777-781
Number of pages5
JournalCHIMIA
Volume67
Issue number11
DOIs
Publication statusPublished - 1 Nov 2013

Keywords

  • biotransformations
  • enzyme-catalyzed atom transfer radical polymerization
  • mechanoresponsive materials
  • nanoreactors
  • polymer-protein hybrid materials

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