Combined treatment of biomatrices with nisin and pulsed electric fields as a potential decontamination method?

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Abstract

Pulsed electric field (PEF) treatment has been shown to achieve bacterial inactivation in collagen gels whilst retaining the ability of the collagen to function as a biomaterial [1, 2]. Nisin, an antimicrobial peptide, has been used widely as a food preservative and has shown bactericidal action against a number of Gram-positive bacteria [3]. The potential of nisin to increase the efficacy of PEF disinfection of collagen gels to be used for tissue engineering applications was investigated.
Original languageEnglish
Pages (from-to)18
Number of pages1
JournalEuropean Cells and Materials
Volume18
Issue numberSuppl. 2
Publication statusPublished - 2009

Keywords

  • biomatrices
  • nisin
  • pulsed electric fields
  • decontamination
  • biomaterials
  • cells

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