Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy

Sarah J Stock; Jade Carruthers; Cheryl Denny; Jack Donaghy; Anna Goulding; Lisa E M Hopcroft; Leanne Hopkins; Rachel Mulholland; Utkarsh Agrawal; Bonnie Auyeung; Srinivasa Vittal Katikireddi; Colin McCowan; Josie Murray; Chris Robertson; Aziz Sheikh; Ting Shi; Colin R Simpson; Eleftheria Vasileiou; Rachael Wood

doi:10.1093/ije/dyab243

Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy

Sarah J Stock, Jade Carruthers, Cheryl Denny, Jack Donaghy, Anna Goulding, Lisa E M Hopcroft, Leanne Hopkins, Rachel Mulholland, Utkarsh Agrawal, Bonnie Auyeung, Srinivasa Vittal Katikireddi, Colin McCowan, Josie Murray, Chris Robertson, Aziz Sheikh, Ting Shi, Colin R Simpson, Eleftheria Vasileiou, Rachael Wood

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Abstract

COVID-19 in Pregnancy in Scotland (COPS) is a new national prospective dynamic cohort that was created to describe the epidemiology of COVID-19 in pregnancy and the effect of SARS-CoV-2 infection on pregnancy outcomes and to investigate the safety and effectiveness of COVID-19 vaccines among pregnant women.

The cohort links primary care records to maternity records, national birth and mortality records and other secondary health care data, together with laboratory results and vaccination information, thus providing a robust platform for the study of viral effects and pharmacoepidemiological research.

As of 16 September 2021, the dynamic cohort included 123 004 women with 134 070 completed or ongoing pregnancies. Pre-pandemic outcome rates for analyses can be calculated from an approved retrospective extension of the cohort to 1 January 2015.

Data are hosted in the Public Health Scotland’s (PHS) trusted research environment (TRE) and access may be granted via an enquiry to [phs.edris@phs.scot].

Original language	English
Journal	International Journal of Epidemiology
Early online date	3 Jan 2022
DOIs	https://doi.org/10.1093/ije/dyab243
Publication status	E-pub ahead of print - 3 Jan 2022

Keywords

pregnancy
epidemiology
Covid-19
Scotland

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/ije/dyab243Licence: CC BY 4.0

Stock-etal-IJE-2022-Covid-19-in-pregnancy-in-scotland-cops-dynamic-cohort-of-pregnant-women-to-assess-effectsFinal published version, 901 KBLicence: CC BY 4.0

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Stock, S. J., Carruthers, J., Denny, C., Donaghy, J., Goulding, A., Hopcroft, L. E. M., Hopkins, L., Mulholland, R., Agrawal, U., Auyeung, B., Katikireddi, S. V., McCowan, C., Murray, J., Robertson, C., Sheikh, A., Shi, T., Simpson, C. R., Vasileiou, E., & Wood, R. (2022). Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy. International Journal of Epidemiology. https://doi.org/10.1093/ije/dyab243

Stock, Sarah J ; Carruthers, Jade ; Denny, Cheryl ; Donaghy, Jack ; Goulding, Anna ; Hopcroft, Lisa E M ; Hopkins, Leanne ; Mulholland, Rachel ; Agrawal, Utkarsh ; Auyeung, Bonnie ; Katikireddi, Srinivasa Vittal ; McCowan, Colin ; Murray, Josie ; Robertson, Chris ; Sheikh, Aziz ; Shi, Ting ; Simpson, Colin R ; Vasileiou, Eleftheria ; Wood, Rachael. / Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy. In: International Journal of Epidemiology. 2022.

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title = "Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy",

abstract = "COVID-19 in Pregnancy in Scotland (COPS) is a new national prospective dynamic cohort that was created to describe the epidemiology of COVID-19 in pregnancy and the effect of SARS-CoV-2 infection on pregnancy outcomes and to investigate the safety and effectiveness of COVID-19 vaccines among pregnant women.The cohort links primary care records to maternity records, national birth and mortality records and other secondary health care data, together with laboratory results and vaccination information, thus providing a robust platform for the study of viral effects and pharmacoepidemiological research.As of 16 September 2021, the dynamic cohort included 123 004 women with 134 070 completed or ongoing pregnancies. Pre-pandemic outcome rates for analyses can be calculated from an approved retrospective extension of the cohort to 1 January 2015.Data are hosted in the Public Health Scotland{\textquoteright}s (PHS) trusted research environment (TRE) and access may be granted via an enquiry to [phs.edris@phs.scot].",

keywords = "pregnancy, epidemiology, Covid-19, Scotland",

author = "Stock, {Sarah J} and Jade Carruthers and Cheryl Denny and Jack Donaghy and Anna Goulding and Hopcroft, {Lisa E M} and Leanne Hopkins and Rachel Mulholland and Utkarsh Agrawal and Bonnie Auyeung and Katikireddi, {Srinivasa Vittal} and Colin McCowan and Josie Murray and Chris Robertson and Aziz Sheikh and Ting Shi and Simpson, {Colin R} and Eleftheria Vasileiou and Rachael Wood",

year = "2022",

month = jan,

day = "3",

doi = "10.1093/ije/dyab243",

language = "English",

journal = "International Journal of Epidemiology",

issn = "0300-5771",

publisher = "Oxford University Press",

}

Stock, SJ, Carruthers, J, Denny, C, Donaghy, J, Goulding, A, Hopcroft, LEM, Hopkins, L, Mulholland, R, Agrawal, U, Auyeung, B, Katikireddi, SV, McCowan, C, Murray, J, Robertson, C, Sheikh, A, Shi, T, Simpson, CR, Vasileiou, E & Wood, R 2022, 'Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy', International Journal of Epidemiology. https://doi.org/10.1093/ije/dyab243

Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy. / Stock, Sarah J; Carruthers, Jade; Denny, Cheryl; Donaghy, Jack; Goulding, Anna; Hopcroft, Lisa E M; Hopkins, Leanne; Mulholland, Rachel; Agrawal, Utkarsh; Auyeung, Bonnie; Katikireddi, Srinivasa Vittal; McCowan, Colin; Murray, Josie; Robertson, Chris; Sheikh, Aziz; Shi, Ting; Simpson, Colin R; Vasileiou, Eleftheria; Wood, Rachael.

In: International Journal of Epidemiology, 03.01.2022.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy

AU - Stock, Sarah J

AU - Carruthers, Jade

AU - Denny, Cheryl

AU - Donaghy, Jack

AU - Goulding, Anna

AU - Hopcroft, Lisa E M

AU - Hopkins, Leanne

AU - Mulholland, Rachel

AU - Agrawal, Utkarsh

AU - Auyeung, Bonnie

AU - Katikireddi, Srinivasa Vittal

AU - McCowan, Colin

AU - Murray, Josie

AU - Robertson, Chris

AU - Sheikh, Aziz

AU - Shi, Ting

AU - Simpson, Colin R

AU - Vasileiou, Eleftheria

AU - Wood, Rachael

PY - 2022/1/3

Y1 - 2022/1/3

N2 - COVID-19 in Pregnancy in Scotland (COPS) is a new national prospective dynamic cohort that was created to describe the epidemiology of COVID-19 in pregnancy and the effect of SARS-CoV-2 infection on pregnancy outcomes and to investigate the safety and effectiveness of COVID-19 vaccines among pregnant women.The cohort links primary care records to maternity records, national birth and mortality records and other secondary health care data, together with laboratory results and vaccination information, thus providing a robust platform for the study of viral effects and pharmacoepidemiological research.As of 16 September 2021, the dynamic cohort included 123 004 women with 134 070 completed or ongoing pregnancies. Pre-pandemic outcome rates for analyses can be calculated from an approved retrospective extension of the cohort to 1 January 2015.Data are hosted in the Public Health Scotland’s (PHS) trusted research environment (TRE) and access may be granted via an enquiry to [phs.edris@phs.scot].

AB - COVID-19 in Pregnancy in Scotland (COPS) is a new national prospective dynamic cohort that was created to describe the epidemiology of COVID-19 in pregnancy and the effect of SARS-CoV-2 infection on pregnancy outcomes and to investigate the safety and effectiveness of COVID-19 vaccines among pregnant women.The cohort links primary care records to maternity records, national birth and mortality records and other secondary health care data, together with laboratory results and vaccination information, thus providing a robust platform for the study of viral effects and pharmacoepidemiological research.As of 16 September 2021, the dynamic cohort included 123 004 women with 134 070 completed or ongoing pregnancies. Pre-pandemic outcome rates for analyses can be calculated from an approved retrospective extension of the cohort to 1 January 2015.Data are hosted in the Public Health Scotland’s (PHS) trusted research environment (TRE) and access may be granted via an enquiry to [phs.edris@phs.scot].

KW - pregnancy

KW - epidemiology

KW - Covid-19

KW - Scotland

U2 - 10.1093/ije/dyab243

DO - 10.1093/ije/dyab243

M3 - Article

JO - International Journal of Epidemiology

JF - International Journal of Epidemiology

SN - 0300-5771

ER -

Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy

Abstract

Keywords

UN SDGs

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