CMRI based 3D left ventricle motion analysis on patients with acute myocardial infarction

Hao Gao, K Kushsairy Bin Abdul Kadir, A. Payne, C. Berry, John Soraghan, X Lou

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

Abstract

3D Quantitative measurement of left ventricle (LV) motion on patients with acute myocardial infarction has been recognized as essential for effective LV function diagnosis. This paper presents a method to quantify 3D LV motion obtained from conventional CINE MRI using image analysis based on mathematical modeling. Level set method is employed for segmentation, and a 3D LV geometry was reconstructed by co-registering different views of MRI images. A mathematical model of LV geometry was then constructed to quantitatively describe the LV wall inward motion. The results using real data show that the method is able to quantify the LV inward motion, and can clearly represent the changed motion pattern with the follow-up data. Furthermore, the LV motion analysis for 8 patients with acute myocardial infarction (MI) show that high inward motion occurs mainly in the basal region of LV while a negative relation is found between LV eject fraction improvement after acute MI and solely basal region inward motion, which could be helpful for diagnosis and LV EF recovery prediction.
Original languageEnglish
Title of host publicationProceedings from the 33rd Annual International IEEE Engineering in Medicine and Biology Society Conference 2011
Place of PublicationBoston, USA
PublisherIEEE
Publication statusPublished - 2011

Fingerprint

Magnetic resonance imaging
Geometry
Image analysis
Mathematical models
Recovery
Motion analysis

Keywords

  • cardiac modeling
  • ventricular mechanics
  • cardiac MRI

Cite this

Gao, H., Kushsairy Bin Abdul Kadir, K., Payne, A., Berry, C., Soraghan, J., & Lou, X. (2011). CMRI based 3D left ventricle motion analysis on patients with acute myocardial infarction. In Proceedings from the 33rd Annual International IEEE Engineering in Medicine and Biology Society Conference 2011 Boston, USA: IEEE.
Gao, Hao ; Kushsairy Bin Abdul Kadir, K ; Payne, A. ; Berry, C. ; Soraghan, John ; Lou, X. / CMRI based 3D left ventricle motion analysis on patients with acute myocardial infarction. Proceedings from the 33rd Annual International IEEE Engineering in Medicine and Biology Society Conference 2011. Boston, USA : IEEE, 2011.
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title = "CMRI based 3D left ventricle motion analysis on patients with acute myocardial infarction",
abstract = "3D Quantitative measurement of left ventricle (LV) motion on patients with acute myocardial infarction has been recognized as essential for effective LV function diagnosis. This paper presents a method to quantify 3D LV motion obtained from conventional CINE MRI using image analysis based on mathematical modeling. Level set method is employed for segmentation, and a 3D LV geometry was reconstructed by co-registering different views of MRI images. A mathematical model of LV geometry was then constructed to quantitatively describe the LV wall inward motion. The results using real data show that the method is able to quantify the LV inward motion, and can clearly represent the changed motion pattern with the follow-up data. Furthermore, the LV motion analysis for 8 patients with acute myocardial infarction (MI) show that high inward motion occurs mainly in the basal region of LV while a negative relation is found between LV eject fraction improvement after acute MI and solely basal region inward motion, which could be helpful for diagnosis and LV EF recovery prediction.",
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author = "Hao Gao and {Kushsairy Bin Abdul Kadir}, K and A. Payne and C. Berry and John Soraghan and X Lou",
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Gao, H, Kushsairy Bin Abdul Kadir, K, Payne, A, Berry, C, Soraghan, J & Lou, X 2011, CMRI based 3D left ventricle motion analysis on patients with acute myocardial infarction. in Proceedings from the 33rd Annual International IEEE Engineering in Medicine and Biology Society Conference 2011. IEEE, Boston, USA.

CMRI based 3D left ventricle motion analysis on patients with acute myocardial infarction. / Gao, Hao; Kushsairy Bin Abdul Kadir, K; Payne, A.; Berry, C.; Soraghan, John; Lou, X.

Proceedings from the 33rd Annual International IEEE Engineering in Medicine and Biology Society Conference 2011. Boston, USA : IEEE, 2011.

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

TY - GEN

T1 - CMRI based 3D left ventricle motion analysis on patients with acute myocardial infarction

AU - Gao, Hao

AU - Kushsairy Bin Abdul Kadir, K

AU - Payne, A.

AU - Berry, C.

AU - Soraghan, John

AU - Lou, X

PY - 2011

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N2 - 3D Quantitative measurement of left ventricle (LV) motion on patients with acute myocardial infarction has been recognized as essential for effective LV function diagnosis. This paper presents a method to quantify 3D LV motion obtained from conventional CINE MRI using image analysis based on mathematical modeling. Level set method is employed for segmentation, and a 3D LV geometry was reconstructed by co-registering different views of MRI images. A mathematical model of LV geometry was then constructed to quantitatively describe the LV wall inward motion. The results using real data show that the method is able to quantify the LV inward motion, and can clearly represent the changed motion pattern with the follow-up data. Furthermore, the LV motion analysis for 8 patients with acute myocardial infarction (MI) show that high inward motion occurs mainly in the basal region of LV while a negative relation is found between LV eject fraction improvement after acute MI and solely basal region inward motion, which could be helpful for diagnosis and LV EF recovery prediction.

AB - 3D Quantitative measurement of left ventricle (LV) motion on patients with acute myocardial infarction has been recognized as essential for effective LV function diagnosis. This paper presents a method to quantify 3D LV motion obtained from conventional CINE MRI using image analysis based on mathematical modeling. Level set method is employed for segmentation, and a 3D LV geometry was reconstructed by co-registering different views of MRI images. A mathematical model of LV geometry was then constructed to quantitatively describe the LV wall inward motion. The results using real data show that the method is able to quantify the LV inward motion, and can clearly represent the changed motion pattern with the follow-up data. Furthermore, the LV motion analysis for 8 patients with acute myocardial infarction (MI) show that high inward motion occurs mainly in the basal region of LV while a negative relation is found between LV eject fraction improvement after acute MI and solely basal region inward motion, which could be helpful for diagnosis and LV EF recovery prediction.

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Gao H, Kushsairy Bin Abdul Kadir K, Payne A, Berry C, Soraghan J, Lou X. CMRI based 3D left ventricle motion analysis on patients with acute myocardial infarction. In Proceedings from the 33rd Annual International IEEE Engineering in Medicine and Biology Society Conference 2011. Boston, USA: IEEE. 2011