Clarification of route specific impurities found in methylamphetamine synthesised using the Birch method

Vanitha Kunalan, William Kerr, Niamh Nic Daeid

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This paper focuses on the determination of route specific impurities produced when methylamphetamine is synthesised using the Birch reduction. Previous work available in the scientific literature reported only one route specific impurity using ephedrine hydrochloride as the starting material. In this paper we investigated the impurity profiles of methylamphetamine produced from both the salt and base forms of ephedrine and pseudoephedrine. A new previously unreported route specific impurity was revealed as was the potential absence of the previously reported impurity in the profile of samples prepared from the free base.
LanguageEnglish
Pages321-329
Number of pages9
JournalForensic Science International
Volume223
Issue number1-3
DOIs
Publication statusPublished - 30 Nov 2012

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Ephedrine
Betula
Methamphetamine
Pseudoephedrine
Literature
Salts

Keywords

  • Birch reduction
  • methylamphetamine
  • route specific impurities

Cite this

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Clarification of route specific impurities found in methylamphetamine synthesised using the Birch method. / Kunalan, Vanitha; Kerr, William; Nic Daeid, Niamh.

In: Forensic Science International, Vol. 223, No. 1-3, 30.11.2012, p. 321-329.

Research output: Contribution to journalArticle

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