Chlorothiazide N,N-dimethylacetamidedisolvate

Andrea Johnston, Alastair J. Florence, Philippe Fernandes, Alan R. Kennedy

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Chlorothiazide forms a 1:2 solvate with N,N-dimethylacetamide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide N,N-dimethylacetamide disolvate), C7H6ClN3O4S2·2C4H9NO. The compound crystallizes with one chlorothiazide and two solvent molecules in the asymmetric unit, forming three intermolecular N-HO hydrogen bonds.
LanguageEnglish
PagesO2422-U770
Number of pages12
JournalActa Crystallographica Section E: Structure Reports
Volume63
DOIs
Publication statusPublished - May 2007

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Chlorothiazide
dioxides
Hydrogen bonds
Benzothiadiazines
hydrogen bonds
Molecules
Sulfonamides
molecules
dimethylacetamide

Keywords

  • crystallization
  • chlorothiazide

Cite this

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title = "Chlorothiazide N,N-dimethylacetamidedisolvate",
abstract = "Chlorothiazide forms a 1:2 solvate with N,N-dimethylacetamide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide N,N-dimethylacetamide disolvate), C7H6ClN3O4S2·2C4H9NO. The compound crystallizes with one chlorothiazide and two solvent molecules in the asymmetric unit, forming three intermolecular N-HO hydrogen bonds.",
keywords = "crystallization, chlorothiazide",
author = "Andrea Johnston and Florence, {Alastair J.} and Philippe Fernandes and Kennedy, {Alan R.}",
year = "2007",
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language = "English",
volume = "63",
pages = "O2422--U770",
journal = "Acta Crystallographica Section E: Structure Reports",
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Chlorothiazide N,N-dimethylacetamidedisolvate. / Johnston, Andrea; Florence, Alastair J.; Fernandes, Philippe; Kennedy, Alan R.

In: Acta Crystallographica Section E: Structure Reports, Vol. 63, 05.2007, p. O2422-U770.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Chlorothiazide N,N-dimethylacetamidedisolvate

AU - Johnston, Andrea

AU - Florence, Alastair J.

AU - Fernandes, Philippe

AU - Kennedy, Alan R.

PY - 2007/5

Y1 - 2007/5

N2 - Chlorothiazide forms a 1:2 solvate with N,N-dimethylacetamide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide N,N-dimethylacetamide disolvate), C7H6ClN3O4S2·2C4H9NO. The compound crystallizes with one chlorothiazide and two solvent molecules in the asymmetric unit, forming three intermolecular N-HO hydrogen bonds.

AB - Chlorothiazide forms a 1:2 solvate with N,N-dimethylacetamide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide N,N-dimethylacetamide disolvate), C7H6ClN3O4S2·2C4H9NO. The compound crystallizes with one chlorothiazide and two solvent molecules in the asymmetric unit, forming three intermolecular N-HO hydrogen bonds.

KW - crystallization

KW - chlorothiazide

U2 - 10.1107/S1600536807016388

DO - 10.1107/S1600536807016388

M3 - Article

VL - 63

SP - O2422-U770

JO - Acta Crystallographica Section E: Structure Reports

T2 - Acta Crystallographica Section E: Structure Reports

JF - Acta Crystallographica Section E: Structure Reports

SN - 1600-5368

ER -