Chlorothiazide dimethyl sulfoxide solvate

Andrea Johnston; Alastair J. Florence; Philippe Fernandes; Alan R. Kennedy

doi:10.1107/S1600536807016406

Chlorothiazide dimethyl sulfoxide solvate

Andrea Johnston, Alastair J. Florence, Philippe Fernandes, Alan R. Kennedy

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Chlorothiazide forms a 1:1 solvate with dimethyl sulfoxide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethyl sulfoxide solvate), C7H6ClN3O4S2·C2H6OS. The compound crystallizes with two molecules of solvent and two molecules of chlorothiazide in the asymmetric unit and displays an extensive network of hydrogen bonds.

Original language	English
Pages (from-to)	O2423-U781
Number of pages	12
Journal	Acta Crystallographica Section E: Structure Reports
Volume	63
DOIs	https://doi.org/10.1107/S1600536807016406
Publication status	Published - May 2007

Keywords

crystallization
chlorothiazide
sulfoxide solvate
hydrogen bonds

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10.1107/S1600536807016406

x-ray diffractometer
Kennedy, A.
Pure And Applied Chemistry
Facility/equipment: Equipment

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title = "Chlorothiazide dimethyl sulfoxide solvate",

abstract = "Chlorothiazide forms a 1:1 solvate with dimethyl sulfoxide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethyl sulfoxide solvate), C7H6ClN3O4S2·C2H6OS. The compound crystallizes with two molecules of solvent and two molecules of chlorothiazide in the asymmetric unit and displays an extensive network of hydrogen bonds.",

keywords = "crystallization, chlorothiazide , sulfoxide solvate, hydrogen bonds",

author = "Andrea Johnston and Florence, \{Alastair J.\} and Philippe Fernandes and Kennedy, \{Alan R.\}",

year = "2007",

month = may,

doi = "10.1107/S1600536807016406",

language = "English",

volume = "63",

pages = "O2423--U781",

journal = "Acta Crystallographica Section E: Structure Reports",

issn = "1600-5368",

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TY - JOUR

T1 - Chlorothiazide dimethyl sulfoxide solvate

AU - Johnston, Andrea

AU - Florence, Alastair J.

AU - Fernandes, Philippe

AU - Kennedy, Alan R.

PY - 2007/5

Y1 - 2007/5

N2 - Chlorothiazide forms a 1:1 solvate with dimethyl sulfoxide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethyl sulfoxide solvate), C7H6ClN3O4S2·C2H6OS. The compound crystallizes with two molecules of solvent and two molecules of chlorothiazide in the asymmetric unit and displays an extensive network of hydrogen bonds.

AB - Chlorothiazide forms a 1:1 solvate with dimethyl sulfoxide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethyl sulfoxide solvate), C7H6ClN3O4S2·C2H6OS. The compound crystallizes with two molecules of solvent and two molecules of chlorothiazide in the asymmetric unit and displays an extensive network of hydrogen bonds.

KW - crystallization

KW - chlorothiazide

KW - sulfoxide solvate

KW - hydrogen bonds

U2 - 10.1107/S1600536807016406

DO - 10.1107/S1600536807016406

M3 - Article

SN - 1600-5368

VL - 63

SP - O2423-U781

JO - Acta Crystallographica Section E: Structure Reports

JF - Acta Crystallographica Section E: Structure Reports

ER -

Chlorothiazide dimethyl sulfoxide solvate

Abstract

Keywords

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