Chlorothiazide dimethyl sulfoxide solvate

Andrea Johnston, Alastair J. Florence, Philippe Fernandes, Alan R. Kennedy

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Chlorothiazide forms a 1:1 solvate with dimethyl sulfoxide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethyl sulfoxide solvate), C7H6ClN3O4S2·C2H6OS. The compound crystallizes with two molecules of solvent and two molecules of chlorothiazide in the asymmetric unit and displays an extensive network of hydrogen bonds.
LanguageEnglish
PagesO2423-U781
Number of pages12
JournalActa Crystallographica Section E: Structure Reports
Volume63
DOIs
Publication statusPublished - May 2007

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Chlorothiazide
Dimethyl sulfoxide
Dimethyl Sulfoxide
Benzothiadiazines
Molecules
Sulfonamides
dioxides
molecules
Hydrogen bonds
hydrogen bonds

Keywords

  • crystallization
  • chlorothiazide
  • sulfoxide solvate
  • hydrogen bonds

Cite this

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Chlorothiazide dimethyl sulfoxide solvate. / Johnston, Andrea; Florence, Alastair J.; Fernandes, Philippe; Kennedy, Alan R.

In: Acta Crystallographica Section E: Structure Reports, Vol. 63, 05.2007, p. O2423-U781.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Chlorothiazide dimethyl sulfoxide solvate

AU - Johnston, Andrea

AU - Florence, Alastair J.

AU - Fernandes, Philippe

AU - Kennedy, Alan R.

PY - 2007/5

Y1 - 2007/5

N2 - Chlorothiazide forms a 1:1 solvate with dimethyl sulfoxide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethyl sulfoxide solvate), C7H6ClN3O4S2·C2H6OS. The compound crystallizes with two molecules of solvent and two molecules of chlorothiazide in the asymmetric unit and displays an extensive network of hydrogen bonds.

AB - Chlorothiazide forms a 1:1 solvate with dimethyl sulfoxide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethyl sulfoxide solvate), C7H6ClN3O4S2·C2H6OS. The compound crystallizes with two molecules of solvent and two molecules of chlorothiazide in the asymmetric unit and displays an extensive network of hydrogen bonds.

KW - crystallization

KW - chlorothiazide

KW - sulfoxide solvate

KW - hydrogen bonds

U2 - 10.1107/S1600536807016406

DO - 10.1107/S1600536807016406

M3 - Article

VL - 63

SP - O2423-U781

JO - Acta Crystallographica Section E: Structure Reports

T2 - Acta Crystallographica Section E: Structure Reports

JF - Acta Crystallographica Section E: Structure Reports

SN - 1600-5368

ER -