@article{dc82ff749af7405a90078eb7881739d8,
title = "Chemoselective Suzuki-Miyaura cross-coupling via kinetic transmetallation",
abstract = "Chemoselective Suzuki-Miyaura cross-coupling generally requires a designed deactivation of one nucleophile towards transmetallation. Here we show that boronic acids can be chemoselectively reacted in the presence of ostensibly equivalently reactive boronic acid pinacol (BPin) esters by kinetic discrimination during transmetallation. Simultaneous electrophile control allows sequential chemoselective cross-couplings in a single operation in the absence of protecting groups.",
keywords = "multinucleophile systems, chemical synthesis, chemoselectivity, organoborons, arylboron nucleophiles, transmetallation, kinetic discrimination, Suzuki-Miyaura reaction, boron, cross-coupling, palladium",
author = "Fyfe, {James W. B.} and Fazakerley, {Neal J.} and Watson, {Allan J. B.}",
note = "{\textcopyright} 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim J. W. B. Fyfe, N. J. Fazakerley, A. J. B. Watson, Angew. Chem. Int. Ed. 2017, 56, 1249., https://doi.org/10.1002/anie.201610797 This is the peer reviewed version of the following article: Fyfe, J. W. B., Fazakerley, N. J., & Watson, A. J. B. (2016). Chemoselective Suzuki-Miyaura cross-coupling via kinetic transmetallation. Angewandte Chemie International Edition, which will be published in final form at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-3773. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.",
year = "2017",
month = jan,
day = "24",
doi = "10.1002/anie.201610797",
language = "English",
volume = "56",
pages = "1249--1253",
journal = "Angewandte Chemie International Edition",
issn = "1433-7851",
publisher = "John Wiley and Sons Ltd",
number = "5",
}