Characterization of wax granules containing paracetamol produced by a hot-melt spray system

G.H. Coombs, H.N.E. Stevens, B. Thorne, A. Mullen

Research output: Contribution to journalArticlepeer-review


Paracetamol of different particle-size ranges was incorporated into glyceryl monostearate (GMS) granules with the anticipation of producing a sustained-release oral delivery system from a hot-melt solid dispersion (Habib 2001). Subsequent characterization of these formulations indicated that drug release was dependent on particle size but not as anticipated by Noyes-Whitney (Martin et al 1983).
Original languageEnglish
Pages (from-to)A61-A61
JournalJournal of Pharmacy and Pharmacology
Issue numberS1
Publication statusPublished - 2008


  • wax granules
  • paracetamol
  • hot melt spray system

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