Characterization of wax granules containing paracetamol produced by a hot-melt spray system

G.H. Coombs; H.N.E. Stevens; B. Thorne; A. Mullen

doi:10.1211/002235708785623327

Characterization of wax granules containing paracetamol produced by a hot-melt spray system

G.H. Coombs, H.N.E. Stevens, B. Thorne, A. Mullen

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Paracetamol of different particle-size ranges was incorporated into glyceryl monostearate (GMS) granules with the anticipation of producing a sustained-release oral delivery system from a hot-melt solid dispersion (Habib 2001). Subsequent characterization of these formulations indicated that drug release was dependent on particle size but not as anticipated by Noyes-Whitney (Martin et al 1983).

Original language	English
Pages (from-to)	A61-A61
Journal	Journal of Pharmacy and Pharmacology
Volume	60
Issue number	S1
DOIs	https://doi.org/10.1211/002235708785623327
Publication status	Published - 2008

Keywords

wax granules
paracetamol
hot melt spray system

Access to Document

10.1211/002235708785623327

http://dx.doi.org/10.1211/002235708785623327

Cite this

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title = "Characterization of wax granules containing paracetamol produced by a hot-melt spray system",

abstract = "Paracetamol of different particle-size ranges was incorporated into glyceryl monostearate (GMS) granules with the anticipation of producing a sustained-release oral delivery system from a hot-melt solid dispersion (Habib 2001). Subsequent characterization of these formulations indicated that drug release was dependent on particle size but not as anticipated by Noyes-Whitney (Martin et al 1983).",

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AU - Coombs, G.H.

AU - Stevens, H.N.E.

AU - Thorne, B.

AU - Mullen, A.

PY - 2008

Y1 - 2008

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AB - Paracetamol of different particle-size ranges was incorporated into glyceryl monostearate (GMS) granules with the anticipation of producing a sustained-release oral delivery system from a hot-melt solid dispersion (Habib 2001). Subsequent characterization of these formulations indicated that drug release was dependent on particle size but not as anticipated by Noyes-Whitney (Martin et al 1983).

KW - wax granules

KW - paracetamol

KW - hot melt spray system

UR - http://dx.doi.org/10.1211/002235708785623327

U2 - 10.1211/002235708785623327

DO - 10.1211/002235708785623327

M3 - Article

VL - 60

SP - A61-A61

JO - Journal of Pharmacy and Pharmacology

JF - Journal of Pharmacy and Pharmacology

SN - 0022-3573

IS - S1

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