Characterization of polymeric nanoparticle-protein interactions

Karim Daramy; Caterina Minelli; Yvonne Perrie; Zahra Rattray

Characterization of polymeric nanoparticle-protein interactions

Karim Daramy, Caterina Minelli, Yvonne Perrie, Zahra Rattray

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to conference › Poster › peer-review

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Abstract

Polymeric nanoparticles have shown significant potential for the development of new medicines for unmet clinical need. Upon administration into protein-containing media, proteins will spontaneously adsorb onto the surface of nanoparticles and form a 'protein corona'. Protein corona formation alters the physiochemical properties of nanoparticles which consequently impacts their biological fate. The aim of this study was to develop a robust pipeline for the reproducible characterization of polymeric nanoparticles following protein corona formation.

Original language	English
Number of pages	1
Publication status	Published - 20 Oct 2021
Event	American Association of Pharmaceutical Scientists 2021: PharmSci 360 - Boston Convention & Exhibition Center, Philadelphia, United States Duration: 17 Oct 2021 → 20 Oct 2021 https://www.aaps.org/pharmsci/annual-meeting

Conference

Conference	American Association of Pharmaceutical Scientists 2021
Abbreviated title	AAPS 2021 PharmSci 360
Country/Territory	United States
City	Philadelphia
Period	17/10/21 → 20/10/21
Internet address	https://www.aaps.org/pharmsci/annual-meeting

Keywords

nanoparticle
nanoparticle-protein

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Daramy-etal-AAPS-2021-Characterization-of-polymeric-nanoparticle-protein-interactionsAccepted author manuscript, 0.98 MB

Cite this

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title = "Characterization of polymeric nanoparticle-protein interactions",

abstract = "Polymeric nanoparticles have shown significant potential for the development of new medicines for unmet clinical need. Upon administration into protein-containing media, proteins will spontaneously adsorb onto the surface of nanoparticles and form a 'protein corona'. Protein corona formation alters the physiochemical properties of nanoparticles which consequently impacts their biological fate. The aim of this study was to develop a robust pipeline for the reproducible characterization of polymeric nanoparticles following protein corona formation. ",

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TY - CONF

T1 - Characterization of polymeric nanoparticle-protein interactions

AU - Daramy, Karim

AU - Minelli, Caterina

AU - Perrie, Yvonne

AU - Rattray, Zahra

PY - 2021/10/20

Y1 - 2021/10/20

N2 - Polymeric nanoparticles have shown significant potential for the development of new medicines for unmet clinical need. Upon administration into protein-containing media, proteins will spontaneously adsorb onto the surface of nanoparticles and form a 'protein corona'. Protein corona formation alters the physiochemical properties of nanoparticles which consequently impacts their biological fate. The aim of this study was to develop a robust pipeline for the reproducible characterization of polymeric nanoparticles following protein corona formation.

AB - Polymeric nanoparticles have shown significant potential for the development of new medicines for unmet clinical need. Upon administration into protein-containing media, proteins will spontaneously adsorb onto the surface of nanoparticles and form a 'protein corona'. Protein corona formation alters the physiochemical properties of nanoparticles which consequently impacts their biological fate. The aim of this study was to develop a robust pipeline for the reproducible characterization of polymeric nanoparticles following protein corona formation.

KW - nanoparticle

KW - nanoparticle-protein

UR - https://www.aaps.org/pharmsci/annual-meeting

M3 - Poster

T2 - American Association of Pharmaceutical Scientists 2021

Y2 - 17 October 2021 through 20 October 2021

ER -

Characterization of polymeric nanoparticle-protein interactions

Abstract

Conference

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Doctoral Training Partnership 2018-19 University of Strathclyde | Daramy, Karim

NTA - NS300

Characterisation of Polymeric Nanoparticle-Protein Interactions

Cite this

Characterization of polymeric nanoparticle-protein interactions

Abstract

Conference

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Projects

Doctoral Training Partnership 2018-19 University of Strathclyde | Daramy, Karim

Equipment

NTA - NS300

Activities

Characterisation of Polymeric Nanoparticle-Protein Interactions

Cite this