C–H functionalization for hydrogen isotope exchange

Jens Atzrodt, Volker Derdau, William J. Kerr, Marc Reid

Research output: Contribution to journalLiterature reviewpeer-review

310 Citations (Scopus)
110 Downloads (Pure)


The varied applications of hydrogen isotopes (deuterium, D, and tritium, T) in the physical and life sciences demands a range of methods for their installation in an array of molecular architectures. In this review, we describe recent advances in synthetic C–H functionalization for hydrogen isotope exchange.
Original languageEnglish
Pages (from-to)1-27
Number of pages27
JournalAngewandte Chemie International Edition
Early online date12 Oct 2017
Publication statusE-pub ahead of print - 12 Oct 2017


  • C–H functionalization
  • hydrogen isotope exchange
  • catalysis
  • drug discovery


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