C–H functionalization for hydrogen isotope exchange

Jens Atzrodt; Volker Derdau; William J. Kerr; Marc Reid

doi:10.1002/anie.201708903

C–H functionalization for hydrogen isotope exchange

Jens Atzrodt, Volker Derdau, William J. Kerr, Marc Reid

Pure And Applied Chemistry

Research output: Contribution to journal › Literature review

70 Citations (Scopus)

18 Downloads (Pure)

Abstract

The varied applications of hydrogen isotopes (deuterium, D, and tritium, T) in the physical and life sciences demands a range of methods for their installation in an array of molecular architectures. In this review, we describe recent advances in synthetic C–H functionalization for hydrogen isotope exchange.

Original language	English
Pages (from-to)	1-27
Number of pages	27
Journal	Angewandte Chemie International Edition
Early online date	12 Oct 2017
DOIs	https://doi.org/10.1002/anie.201708903
Publication status	E-pub ahead of print - 12 Oct 2017

Fingerprint

Isotopes

Hydrogen

Tritium

Deuterium

Keywords

C–H functionalization
hydrogen isotope exchange
catalysis
drug discovery

Cite this

Atzrodt, J., Derdau, V., Kerr, W. J., & Reid, M. (2017). C–H functionalization for hydrogen isotope exchange. Angewandte Chemie International Edition, 1-27. https://doi.org/10.1002/anie.201708903

Atzrodt, Jens ; Derdau, Volker ; Kerr, William J. ; Reid, Marc. / C–H functionalization for hydrogen isotope exchange. In: Angewandte Chemie International Edition. 2017 ; pp. 1-27.

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abstract = "The varied applications of hydrogen isotopes (deuterium, D, and tritium, T) in the physical and life sciences demands a range of methods for their installation in an array of molecular architectures. In this review, we describe recent advances in synthetic C–H functionalization for hydrogen isotope exchange.",

keywords = "C–H functionalization , hydrogen isotope exchange , catalysis, drug discovery",

author = "Jens Atzrodt and Volker Derdau and Kerr, {William J.} and Marc Reid",

note = "This is the peer reviewed version of the following article: Atzrodt, J, Derdau, V, Kerr, WJ & Reid, M 2017, 'C–H functionalization for hydrogen isotope exchange' Angewandte Chemie International Edition, pp. 1-27, which has been published in final form at https://doi.org/10.1002/anie.201708903. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.",

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Atzrodt, J, Derdau, V, Kerr, WJ & Reid, M 2017, 'C–H functionalization for hydrogen isotope exchange', Angewandte Chemie International Edition, pp. 1-27. https://doi.org/10.1002/anie.201708903

C–H functionalization for hydrogen isotope exchange. / Atzrodt, Jens; Derdau, Volker; Kerr, William J.; Reid, Marc.

In: Angewandte Chemie International Edition, 12.10.2017, p. 1-27.

Research output: Contribution to journal › Literature review

TY - JOUR

T1 - C–H functionalization for hydrogen isotope exchange

AU - Atzrodt, Jens

AU - Derdau, Volker

AU - Kerr, William J.

AU - Reid, Marc

N1 - This is the peer reviewed version of the following article: Atzrodt, J, Derdau, V, Kerr, WJ & Reid, M 2017, 'C–H functionalization for hydrogen isotope exchange' Angewandte Chemie International Edition, pp. 1-27, which has been published in final form at https://doi.org/10.1002/anie.201708903. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

PY - 2017/10/12

Y1 - 2017/10/12

N2 - The varied applications of hydrogen isotopes (deuterium, D, and tritium, T) in the physical and life sciences demands a range of methods for their installation in an array of molecular architectures. In this review, we describe recent advances in synthetic C–H functionalization for hydrogen isotope exchange.

AB - The varied applications of hydrogen isotopes (deuterium, D, and tritium, T) in the physical and life sciences demands a range of methods for their installation in an array of molecular architectures. In this review, we describe recent advances in synthetic C–H functionalization for hydrogen isotope exchange.

KW - C–H functionalization

KW - hydrogen isotope exchange

KW - catalysis

KW - drug discovery

UR - http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-3773

U2 - 10.1002/anie.201708903

DO - 10.1002/anie.201708903

M3 - Literature review

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JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition