Cerebral visual dysfunction in prematurely born children attending mainstream school

Catriona Macintyre-Béon, David Young, Gordon N. Dutton, Kate Mitchell, Judith Simpson, Gunter Loffler, Richard Bowman, Ruth Hamilton

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Although premature birth is recognised as a cause of cerebral visual impairment (CVI), which can include cerebral visual dysfunction (CVD), the incidence and nature of CVD in prematurely born children is not known. A prospective, controlled investigation was undertaken of forty-six, mainstream primary school children, prematurely born with gestations of 24.0-34.6 weeks, and of 130 control (term-born) children. Assessments were made of IQ, ophthalmic functions, visual perception and visual attention. Structured history-taking seeking evidence of behavioural features of CVI used a question inventory. Obstetric, neonatal and paediatric medical histories were documented from case records. Fifteen out of forty-six (33 %) of the prematurely born children-"cluster A"-revealed behaviours corresponding with CVD on cluster analysis of the CVI inventory. The whole prematurely born group performed worse than controls on all visual perception tests and all four visual attention tests. Children in cluster A were responsible for this effect, performing worse than controls on all visual perception and visual attention tests except visual closure, while cluster B prematurely born children performed no differently to controls. The prevalence of CVD in these prematurely born children is between 21-47 % (95 % CI), with a pattern similar to "dorsal stream dysfunction". Currently available perceptual tests appear to be unable to identify the specific pattern of problems noted in this group. Many studies have provided evidence of cognitive and intellectual dysfunction in prematurely born children, and it is possible that CVD is a contributor. The CVI inventory is a potential means of identifying and characterising the condition, which can be ameliorated with simple strategies.
LanguageEnglish
Pages89-102
Number of pages14
JournalCanadian Journal of Ophthalmology. Journal Canadien d'Ophtalmologie
Volume127
Issue number2
Early online date31 Aug 2013
DOIs
Publication statusE-pub ahead of print - 31 Aug 2013

Fingerprint

Visual Impairment
Vision Disorders
Visual Attention
Visual Perception
Equipment and Supplies
Pediatrics
Children
Vision
Premature Birth
Cluster Analysis
Obstetrics
Incidence
Closure
History
Pregnancy
Term

Keywords

  • cortical blindness
  • child
  • child, preschool
  • contrast sensitivity
  • depth perception
  • female
  • gestational age
  • humans
  • premature infant
  • male
  • medical history taking
  • perceptual disorders
  • premature birth
  • prevalence
  • prospective studies
  • schools
  • sickness impact profile
  • visual perception

Cite this

Macintyre-Béon, Catriona ; Young, David ; Dutton, Gordon N. ; Mitchell, Kate ; Simpson, Judith ; Loffler, Gunter ; Bowman, Richard ; Hamilton, Ruth. / Cerebral visual dysfunction in prematurely born children attending mainstream school. In: Canadian Journal of Ophthalmology. Journal Canadien d'Ophtalmologie. 2013 ; Vol. 127, No. 2. pp. 89-102.
@article{698d960b90b54877b07509d14790b70b,
title = "Cerebral visual dysfunction in prematurely born children attending mainstream school",
abstract = "Although premature birth is recognised as a cause of cerebral visual impairment (CVI), which can include cerebral visual dysfunction (CVD), the incidence and nature of CVD in prematurely born children is not known. A prospective, controlled investigation was undertaken of forty-six, mainstream primary school children, prematurely born with gestations of 24.0-34.6 weeks, and of 130 control (term-born) children. Assessments were made of IQ, ophthalmic functions, visual perception and visual attention. Structured history-taking seeking evidence of behavioural features of CVI used a question inventory. Obstetric, neonatal and paediatric medical histories were documented from case records. Fifteen out of forty-six (33 {\%}) of the prematurely born children-{"}cluster A{"}-revealed behaviours corresponding with CVD on cluster analysis of the CVI inventory. The whole prematurely born group performed worse than controls on all visual perception tests and all four visual attention tests. Children in cluster A were responsible for this effect, performing worse than controls on all visual perception and visual attention tests except visual closure, while cluster B prematurely born children performed no differently to controls. The prevalence of CVD in these prematurely born children is between 21-47 {\%} (95 {\%} CI), with a pattern similar to {"}dorsal stream dysfunction{"}. Currently available perceptual tests appear to be unable to identify the specific pattern of problems noted in this group. Many studies have provided evidence of cognitive and intellectual dysfunction in prematurely born children, and it is possible that CVD is a contributor. The CVI inventory is a potential means of identifying and characterising the condition, which can be ameliorated with simple strategies.",
keywords = "cortical blindness, child, child, preschool, contrast sensitivity, depth perception, female, gestational age, humans, premature infant, male, medical history taking, perceptual disorders, premature birth, prevalence, prospective studies, schools, sickness impact profile, visual perception",
author = "Catriona Macintyre-B{\'e}on and David Young and Dutton, {Gordon N.} and Kate Mitchell and Judith Simpson and Gunter Loffler and Richard Bowman and Ruth Hamilton",
year = "2013",
month = "8",
day = "31",
doi = "10.1007/s10633-013-9405-y",
language = "English",
volume = "127",
pages = "89--102",
journal = "Canadian Journal of Ophthalmology. Journal Canadien d'Ophtalmologie",
issn = "0008-4182",
publisher = "Canadian Ophthalmological Society",
number = "2",

}

Cerebral visual dysfunction in prematurely born children attending mainstream school. / Macintyre-Béon, Catriona; Young, David; Dutton, Gordon N.; Mitchell, Kate; Simpson, Judith; Loffler, Gunter; Bowman, Richard; Hamilton, Ruth.

In: Canadian Journal of Ophthalmology. Journal Canadien d'Ophtalmologie, Vol. 127, No. 2, 31.08.2013, p. 89-102.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Cerebral visual dysfunction in prematurely born children attending mainstream school

AU - Macintyre-Béon, Catriona

AU - Young, David

AU - Dutton, Gordon N.

AU - Mitchell, Kate

AU - Simpson, Judith

AU - Loffler, Gunter

AU - Bowman, Richard

AU - Hamilton, Ruth

PY - 2013/8/31

Y1 - 2013/8/31

N2 - Although premature birth is recognised as a cause of cerebral visual impairment (CVI), which can include cerebral visual dysfunction (CVD), the incidence and nature of CVD in prematurely born children is not known. A prospective, controlled investigation was undertaken of forty-six, mainstream primary school children, prematurely born with gestations of 24.0-34.6 weeks, and of 130 control (term-born) children. Assessments were made of IQ, ophthalmic functions, visual perception and visual attention. Structured history-taking seeking evidence of behavioural features of CVI used a question inventory. Obstetric, neonatal and paediatric medical histories were documented from case records. Fifteen out of forty-six (33 %) of the prematurely born children-"cluster A"-revealed behaviours corresponding with CVD on cluster analysis of the CVI inventory. The whole prematurely born group performed worse than controls on all visual perception tests and all four visual attention tests. Children in cluster A were responsible for this effect, performing worse than controls on all visual perception and visual attention tests except visual closure, while cluster B prematurely born children performed no differently to controls. The prevalence of CVD in these prematurely born children is between 21-47 % (95 % CI), with a pattern similar to "dorsal stream dysfunction". Currently available perceptual tests appear to be unable to identify the specific pattern of problems noted in this group. Many studies have provided evidence of cognitive and intellectual dysfunction in prematurely born children, and it is possible that CVD is a contributor. The CVI inventory is a potential means of identifying and characterising the condition, which can be ameliorated with simple strategies.

AB - Although premature birth is recognised as a cause of cerebral visual impairment (CVI), which can include cerebral visual dysfunction (CVD), the incidence and nature of CVD in prematurely born children is not known. A prospective, controlled investigation was undertaken of forty-six, mainstream primary school children, prematurely born with gestations of 24.0-34.6 weeks, and of 130 control (term-born) children. Assessments were made of IQ, ophthalmic functions, visual perception and visual attention. Structured history-taking seeking evidence of behavioural features of CVI used a question inventory. Obstetric, neonatal and paediatric medical histories were documented from case records. Fifteen out of forty-six (33 %) of the prematurely born children-"cluster A"-revealed behaviours corresponding with CVD on cluster analysis of the CVI inventory. The whole prematurely born group performed worse than controls on all visual perception tests and all four visual attention tests. Children in cluster A were responsible for this effect, performing worse than controls on all visual perception and visual attention tests except visual closure, while cluster B prematurely born children performed no differently to controls. The prevalence of CVD in these prematurely born children is between 21-47 % (95 % CI), with a pattern similar to "dorsal stream dysfunction". Currently available perceptual tests appear to be unable to identify the specific pattern of problems noted in this group. Many studies have provided evidence of cognitive and intellectual dysfunction in prematurely born children, and it is possible that CVD is a contributor. The CVI inventory is a potential means of identifying and characterising the condition, which can be ameliorated with simple strategies.

KW - cortical blindness

KW - child

KW - child, preschool

KW - contrast sensitivity

KW - depth perception

KW - female

KW - gestational age

KW - humans

KW - premature infant

KW - male

KW - medical history taking

KW - perceptual disorders

KW - premature birth

KW - prevalence

KW - prospective studies

KW - schools

KW - sickness impact profile

KW - visual perception

UR - http://link.springer.com/article/10.1007%2Fs10633-013-9405-y

U2 - 10.1007/s10633-013-9405-y

DO - 10.1007/s10633-013-9405-y

M3 - Article

VL - 127

SP - 89

EP - 102

JO - Canadian Journal of Ophthalmology. Journal Canadien d'Ophtalmologie

T2 - Canadian Journal of Ophthalmology. Journal Canadien d'Ophtalmologie

JF - Canadian Journal of Ophthalmology. Journal Canadien d'Ophtalmologie

SN - 0008-4182

IS - 2

ER -