Cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft

K.H. Smith, A.B. Jozwiak, D.V. Bax, C.M. Kielty, R.A. Black

    Research output: Contribution to conferencePaper

    Abstract

    The aim of this work is to develop an artificial artery for use in bypass surgery. The hybrid artery consists of a porous tubular scaffold made from a polyurethane elastomer. The surface of the polymer is then modified with recombinant proteins in order to encourage the growth of organised layers of vascular cells.

    Conference

    ConferenceTissue Engineering and Regenerative Medicine International Society 2007 TERMIS-EU Chapter Meeting
    CityLondon, United Kingdom
    Period4/09/077/09/07

    Fingerprint

    Polyurethanes
    Extracellular Matrix Proteins
    Blood Vessels
    Arteries
    Elastomers
    Transplants
    Recombinant Proteins
    Polymers
    Growth

    Keywords

    • cellular response
    • polyurethane surface
    • vascular extracellular matrix proteins
    • vascular graft
    • cells

    Cite this

    Smith, K. H., Jozwiak, A. B., Bax, D. V., Kielty, C. M., & Black, R. A. (2007). Cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft. Paper presented at Tissue Engineering and Regenerative Medicine International Society 2007 TERMIS-EU Chapter Meeting, London, United Kingdom, .
    Smith, K.H. ; Jozwiak, A.B. ; Bax, D.V. ; Kielty, C.M. ; Black, R.A. / Cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft. Paper presented at Tissue Engineering and Regenerative Medicine International Society 2007 TERMIS-EU Chapter Meeting, London, United Kingdom, .
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    title = "Cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft",
    abstract = "The aim of this work is to develop an artificial artery for use in bypass surgery. The hybrid artery consists of a porous tubular scaffold made from a polyurethane elastomer. The surface of the polymer is then modified with recombinant proteins in order to encourage the growth of organised layers of vascular cells.",
    keywords = "cellular response, polyurethane surface, vascular extracellular matrix proteins, vascular graft, cells",
    author = "K.H. Smith and A.B. Jozwiak and D.V. Bax and C.M. Kielty and R.A. Black",
    year = "2007",
    language = "English",
    note = "Tissue Engineering and Regenerative Medicine International Society 2007 TERMIS-EU Chapter Meeting ; Conference date: 04-09-2007 Through 07-09-2007",

    }

    Smith, KH, Jozwiak, AB, Bax, DV, Kielty, CM & Black, RA 2007, 'Cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft' Paper presented at Tissue Engineering and Regenerative Medicine International Society 2007 TERMIS-EU Chapter Meeting, London, United Kingdom, 4/09/07 - 7/09/07, .

    Cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft. / Smith, K.H.; Jozwiak, A.B.; Bax, D.V.; Kielty, C.M.; Black, R.A.

    2007. Paper presented at Tissue Engineering and Regenerative Medicine International Society 2007 TERMIS-EU Chapter Meeting, London, United Kingdom, .

    Research output: Contribution to conferencePaper

    TY - CONF

    T1 - Cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft

    AU - Smith, K.H.

    AU - Jozwiak, A.B.

    AU - Bax, D.V.

    AU - Kielty, C.M.

    AU - Black, R.A.

    PY - 2007

    Y1 - 2007

    N2 - The aim of this work is to develop an artificial artery for use in bypass surgery. The hybrid artery consists of a porous tubular scaffold made from a polyurethane elastomer. The surface of the polymer is then modified with recombinant proteins in order to encourage the growth of organised layers of vascular cells.

    AB - The aim of this work is to develop an artificial artery for use in bypass surgery. The hybrid artery consists of a porous tubular scaffold made from a polyurethane elastomer. The surface of the polymer is then modified with recombinant proteins in order to encourage the growth of organised layers of vascular cells.

    KW - cellular response

    KW - polyurethane surface

    KW - vascular extracellular matrix proteins

    KW - vascular graft

    KW - cells

    UR - http://www.termis.org/eu2007/

    UR - http://strathprints.strath.ac.uk/8332/

    M3 - Paper

    ER -

    Smith KH, Jozwiak AB, Bax DV, Kielty CM, Black RA. Cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft. 2007. Paper presented at Tissue Engineering and Regenerative Medicine International Society 2007 TERMIS-EU Chapter Meeting, London, United Kingdom, .