Catalytic oxidative processes in steroid chemistry: allylic oxidation, β-selective epoxidation, alcohol oxidations and remote functionalization reactions

Jorge A. R. Salvador, Samuel M. Silvestre, Vania M. Moreira

Research output: Contribution to journalReview articlepeer-review

48 Citations (Scopus)

Abstract

The preparation of steroids containing oxygenated functions in suitable positions of the steroid nucleus is of great importance and can be achieved by means of several oxidative processes. In this paper allylic oxidation, beta-selective epoxidation, alcohol oxidation and remote functionalization reactions in steroid substrates are reviewed. Focus has been given to catalytic processes because of their major importance from the viewpoint of synthetic organic chemistry.
Original languageEnglish
Pages (from-to)2227-2257
Number of pages31
JournalCurrent Organic Chemistry
Volume10
Issue number17
DOIs
Publication statusPublished - 2006

Keywords

  • keto-DHEA acetate
  • steroids oxidation
  • potassium permanganate
  • t-butyl hydroperosice
  • dydroxylation

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