CARDIOSIM ©: the first Italian software platform for simulation of the cardiovascular system and mechanical circulatory and ventilatory support

Beatrice De Lazzari; Roberto Badagliacca; Domenico Filomena; Silvia Papa; Carmine Dario Vizza; Massimo Capoccia; Claudio De Lazzari

doi:10.3390/bioengineering9080383

CARDIOSIM ©: the first Italian software platform for simulation of the cardiovascular system and mechanical circulatory and ventilatory support

Beatrice De Lazzari^*, Roberto Badagliacca, Domenico Filomena, Silvia Papa, Carmine Dario Vizza, Massimo Capoccia, Claudio De Lazzari

^*Corresponding author for this work

Biomedical Engineering

Research output: Contribution to journal › Review article › peer-review

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Abstract

This review is devoted to presenting the history of the CARDIOSIM© software simulator platform, which was developed in Italy to simulate the human cardiovascular and respiratory systems. The first version of CARDIOSIM© was developed at the Institute of Biomedical Technologies of the National Research Council in Rome. The first platform version published in 1991 ran on a PC with a disk operating system (MS-DOS) and was developed using the Turbo Basic language. The latest version runs on PC with Microsoft Windows 10 operating system; it is implemented in Visual Basic and C++ languages. The platform has a modular structure consisting of seven different general sections, which can be assembled to reproduce the most important pathophysiological conditions. One or more zero-dimensional (0-D) modules have been implemented in the platform for each section. The different modules can be assembled to reproduce part or the whole circulation according to Starling’s law of the heart. Different mechanical ventilatory and circulatory devices have been implemented in the platform, including thoracic artificial lungs, ECMO, IABPs, pulsatile and continuous right and left ventricular assist devices, biventricular pacemakers and biventricular assist devices. CARDIOSIM© is used in clinical and educational environments.

Original language	English
Article number	383
Pages (from-to)	383
Number of pages	17
Journal	Bioengineering
Volume	9
Issue number	8
Early online date	11 Aug 2022
DOIs	https://doi.org/10.3390/bioengineering9080383
Publication status	Published - 11 Aug 2022

Keywords

CARDIOSIM©
numerical simulator
lumped-parameter model
e-learning
mechanical circulatory support
ventilatory
cardiovascular system
heart failure
clinician

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10.3390/bioengineering9080383Licence: CC BY 4.0

De-Lazzari-etal-Bioengineering-2022-CARDIOSIM-the-first-Italian-software-platform-for-simulation-of-the-cardiovascular-systemFinal published version, 1.87 MBLicence: CC BY 4.0

Cite this

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title = "CARDIOSIM {\textcopyright}: the first Italian software platform for simulation of the cardiovascular system and mechanical circulatory and ventilatory support",

abstract = "This review is devoted to presenting the history of the CARDIOSIM{\textcopyright} software simulator platform, which was developed in Italy to simulate the human cardiovascular and respiratory systems. The first version of CARDIOSIM{\textcopyright} was developed at the Institute of Biomedical Technologies of the National Research Council in Rome. The first platform version published in 1991 ran on a PC with a disk operating system (MS-DOS) and was developed using the Turbo Basic language. The latest version runs on PC with Microsoft Windows 10 operating system; it is implemented in Visual Basic and C++ languages. The platform has a modular structure consisting of seven different general sections, which can be assembled to reproduce the most important pathophysiological conditions. One or more zero-dimensional (0-D) modules have been implemented in the platform for each section. The different modules can be assembled to reproduce part or the whole circulation according to Starling{\textquoteright}s law of the heart. Different mechanical ventilatory and circulatory devices have been implemented in the platform, including thoracic artificial lungs, ECMO, IABPs, pulsatile and continuous right and left ventricular assist devices, biventricular pacemakers and biventricular assist devices. CARDIOSIM{\textcopyright} is used in clinical and educational environments.",

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author = "{De Lazzari}, Beatrice and Roberto Badagliacca and Domenico Filomena and Silvia Papa and Vizza, {Carmine Dario} and Massimo Capoccia and {De Lazzari}, Claudio",

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AU - Papa, Silvia

AU - Vizza, Carmine Dario

AU - Capoccia, Massimo

AU - De Lazzari, Claudio

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KW - heart failure

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CARDIOSIM ©: the first Italian software platform for simulation of the cardiovascular system and mechanical circulatory and ventilatory support

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Keywords

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