Carbamazepine N,N-dimethylformamide solvate

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

In the title compound, C15H12N2O·C3H7NO, carbamazepine mol­ecules form the R22(8) N - HO hydrogen-bonded dimer arrangement observed in the crystal structures of each of the four known an­hydro­us polymorphs. The mol­ecules of N,N-di­methyl­form­amide are located between adjacent carbamazepine dimers and form an N - HO hydrogen bond to the anti-oriented NH group of the carbox­amide moiety of carbamazepine.
LanguageEnglish
Pageso1509-o1511
JournalActa Crystallographica Section E: Structure Reports
Volume61
Issue number5
DOIs
Publication statusPublished - 30 Apr 2005

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Dimethylformamide
Carbamazepine
Amides
Dimers
amides
dimers
Polymorphism
Hydrogen bonds
Crystal structure
hydrogen bonds
Hydrogen
crystal structure
hydrogen

Keywords

  • carbamazepine mol­ecules
  • crystal structures
  • an­hydro­us polymorphs
  • hydrogen
  • carbox­amide

Cite this

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title = "Carbamazepine N,N-dimethylformamide solvate",
abstract = "In the title compound, C15H12N2O·C3H7NO, carbamazepine mol­ecules form the R22(8) N - HO hydrogen-bonded dimer arrangement observed in the crystal structures of each of the four known an­hydro­us polymorphs. The mol­ecules of N,N-di­methyl­form­amide are located between adjacent carbamazepine dimers and form an N - HO hydrogen bond to the anti-oriented NH group of the carbox­amide moiety of carbamazepine.",
keywords = "carbamazepine mol­ecules, crystal structures, an­hydro­us polymorphs, hydrogen, carbox­amide",
author = "A. Johnston and A. Florence and A.R. Kennedy",
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language = "English",
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Carbamazepine N,N-dimethylformamide solvate. / Johnston, A.; Florence, A.; Kennedy, A.R.

In: Acta Crystallographica Section E: Structure Reports, Vol. 61, No. 5, 30.04.2005, p. o1509-o1511.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Carbamazepine N,N-dimethylformamide solvate

AU - Johnston, A.

AU - Florence, A.

AU - Kennedy, A.R.

PY - 2005/4/30

Y1 - 2005/4/30

N2 - In the title compound, C15H12N2O·C3H7NO, carbamazepine mol­ecules form the R22(8) N - HO hydrogen-bonded dimer arrangement observed in the crystal structures of each of the four known an­hydro­us polymorphs. The mol­ecules of N,N-di­methyl­form­amide are located between adjacent carbamazepine dimers and form an N - HO hydrogen bond to the anti-oriented NH group of the carbox­amide moiety of carbamazepine.

AB - In the title compound, C15H12N2O·C3H7NO, carbamazepine mol­ecules form the R22(8) N - HO hydrogen-bonded dimer arrangement observed in the crystal structures of each of the four known an­hydro­us polymorphs. The mol­ecules of N,N-di­methyl­form­amide are located between adjacent carbamazepine dimers and form an N - HO hydrogen bond to the anti-oriented NH group of the carbox­amide moiety of carbamazepine.

KW - carbamazepine mol­ecules

KW - crystal structures

KW - an­hydro­us polymorphs

KW - hydrogen

KW - carbox­amide

UR - http://dx.doi.org/10.1107/S1600536805012535

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DO - 10.1107/S1600536805012535

M3 - Article

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SP - o1509-o1511

JO - Acta Crystallographica Section E: Structure Reports

T2 - Acta Crystallographica Section E: Structure Reports

JF - Acta Crystallographica Section E: Structure Reports

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