Carbamazepine furfural hemisolvate

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

In the title compound, C15H12N2O center dot 0.5C(5)H(4)O(2), carbamazepine molecules retain the R-2(2)(8) N-(HO)-O-... hydrogen-bonded dimer arrangement observed in the crystal structures of each of the four known anhydrous polymorphs. The furfural molecule is located between adjacent carbamazepine dimers and is hydrogen bonded to only one of the anti-oriented NH groups available on the dimer.

Original languageEnglish
Pages (from-to)O1777-O1779
Number of pages3
JournalActa Crystallographica Section E: Structure Reports
Volume61
DOIs
Publication statusPublished - Jun 2005

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Furaldehyde
Furfural
Carbamazepine
Dimers
dimers
Hydrogen
Molecules
hydrogen
Polymorphism
molecules
Crystal structure
crystal structure

Keywords

  • crystal structures
  • hydrogen bonding
  • carbamazepine dimers

Cite this

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title = "Carbamazepine furfural hemisolvate",
abstract = "In the title compound, C15H12N2O center dot 0.5C(5)H(4)O(2), carbamazepine molecules retain the R-2(2)(8) N-(HO)-O-... hydrogen-bonded dimer arrangement observed in the crystal structures of each of the four known anhydrous polymorphs. The furfural molecule is located between adjacent carbamazepine dimers and is hydrogen bonded to only one of the anti-oriented NH groups available on the dimer.",
keywords = "crystal structures, hydrogen bonding, carbamazepine dimers",
author = "A Johnston and Florence, {A J} and Kennedy, {A R}",
year = "2005",
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language = "English",
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pages = "O1777--O1779",
journal = "Acta Crystallographica Section E: Structure Reports",
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Carbamazepine furfural hemisolvate. / Johnston, A ; Florence, A J ; Kennedy, A R .

In: Acta Crystallographica Section E: Structure Reports, Vol. 61, 06.2005, p. O1777-O1779.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Carbamazepine furfural hemisolvate

AU - Johnston, A

AU - Florence, A J

AU - Kennedy, A R

PY - 2005/6

Y1 - 2005/6

N2 - In the title compound, C15H12N2O center dot 0.5C(5)H(4)O(2), carbamazepine molecules retain the R-2(2)(8) N-(HO)-O-... hydrogen-bonded dimer arrangement observed in the crystal structures of each of the four known anhydrous polymorphs. The furfural molecule is located between adjacent carbamazepine dimers and is hydrogen bonded to only one of the anti-oriented NH groups available on the dimer.

AB - In the title compound, C15H12N2O center dot 0.5C(5)H(4)O(2), carbamazepine molecules retain the R-2(2)(8) N-(HO)-O-... hydrogen-bonded dimer arrangement observed in the crystal structures of each of the four known anhydrous polymorphs. The furfural molecule is located between adjacent carbamazepine dimers and is hydrogen bonded to only one of the anti-oriented NH groups available on the dimer.

KW - crystal structures

KW - hydrogen bonding

KW - carbamazepine dimers

U2 - 10.1107/s1600536805014984

DO - 10.1107/s1600536805014984

M3 - Article

VL - 61

SP - O1777-O1779

JO - Acta Crystallographica Section E: Structure Reports

JF - Acta Crystallographica Section E: Structure Reports

SN - 1600-5368

ER -