Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa

S.R.M. Ibrahim; R.A. Edrada-Ebel; G.A. Mohamed; D.T.A. Youssef; V. Wray; P. Proksch

Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa

S.R.M. Ibrahim, R.A. Edrada-Ebel, G.A. Mohamed, D.T.A. Youssef, V. Wray, P. Proksch

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

From the ethyl acetate fraction of the Indonesian sponge Callyspongia aerizusa extract, a new cyclic peptide named callyaerin G was isolated. Its structure was elucidated by extensive 1D and 2D NMR (1H NMR, TOCSY and ROESY) studies and mass spectrometric data (ESI- and FAB-MS). The stereochemistry was determined by Marfey's analysis. Callyaerin G was found to exhibit cytotoxic activity when tested against different cancer cell lines.

Original language	English
Pages (from-to)	164-171
Number of pages	7
Journal	ARKIVOC - Online Journal of Organic Chemistry
Publication status	Published - 16 Apr 2008

Keywords

callyspongia aerizusa
callyaerin G
marfey's analysis
cytotoxicity

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This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa",

abstract = "From the ethyl acetate fraction of the Indonesian sponge Callyspongia aerizusa extract, a new cyclic peptide named callyaerin G was isolated. Its structure was elucidated by extensive 1D and 2D NMR (1H NMR, TOCSY and ROESY) studies and mass spectrometric data (ESI- and FAB-MS). The stereochemistry was determined by Marfey's analysis. Callyaerin G was found to exhibit cytotoxic activity when tested against different cancer cell lines.",

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author = "S.R.M. Ibrahim and R.A. Edrada-Ebel and G.A. Mohamed and D.T.A. Youssef and V. Wray and P. Proksch",

year = "2008",

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language = "English",

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journal = "ARKIVOC - Online Journal of Organic Chemistry",

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TY - JOUR

T1 - Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa

AU - Ibrahim, S.R.M.

AU - Edrada-Ebel, R.A.

AU - Mohamed, G.A.

AU - Youssef, D.T.A.

AU - Wray, V.

AU - Proksch, P.

PY - 2008/4/16

Y1 - 2008/4/16

N2 - From the ethyl acetate fraction of the Indonesian sponge Callyspongia aerizusa extract, a new cyclic peptide named callyaerin G was isolated. Its structure was elucidated by extensive 1D and 2D NMR (1H NMR, TOCSY and ROESY) studies and mass spectrometric data (ESI- and FAB-MS). The stereochemistry was determined by Marfey's analysis. Callyaerin G was found to exhibit cytotoxic activity when tested against different cancer cell lines.

AB - From the ethyl acetate fraction of the Indonesian sponge Callyspongia aerizusa extract, a new cyclic peptide named callyaerin G was isolated. Its structure was elucidated by extensive 1D and 2D NMR (1H NMR, TOCSY and ROESY) studies and mass spectrometric data (ESI- and FAB-MS). The stereochemistry was determined by Marfey's analysis. Callyaerin G was found to exhibit cytotoxic activity when tested against different cancer cell lines.

KW - callyspongia aerizusa

KW - callyaerin G

KW - marfey's analysis

KW - cytotoxicity

UR - http://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/2008/12/

M3 - Article

SN - 1551-7004

SP - 164

EP - 171

JO - ARKIVOC - Online Journal of Organic Chemistry

JF - ARKIVOC - Online Journal of Organic Chemistry

ER -

Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa

Abstract

Keywords

UN SDGs

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