C− H functionalisation for hydrogen isotope exchange

Jens Atzrodt, Volker Derdau, William Kerr, Marc Reid

Research output: Contribution to journalReview articlepeer-review

405 Citations (Scopus)
149 Downloads (Pure)

Abstract

The various applications of hydrogen isotopes (deuterium, D, and tritium, T) in the physical and life sciences demand a range of methods for their installation in an array of molecular architectures. In this Review, we describe recent advances in synthetic C−H functionalisation for hydrogen isotope exchange.
Original languageEnglish
Pages (from-to)3022-3047
Number of pages25
JournalAngewandte Chemie International Edition
Volume57
Issue number12
Early online date12 Oct 2017
DOIs
Publication statusPublished - 12 Mar 2018

Keywords

  • C–H functionalization
  • hydrogen isotope exchange
  • catalysis
  • drug discovery

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