Blood flow simulations in models of the pulmonary bifurcation to facilitate treatment of adults with congenital heart disease

Research output: Contribution to conferenceAbstract

Abstract

Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart disease, for which patients require surgical intervention at a very young age. Although these patients have long survival rates, they are at risk of chronic complications and frequently require re-operations with the most common being pulmonary valve replacement (PVR). However, the decision for surgical intervention is currently based on clinical indications and the right timing for PVR remains ambiguous [1,2]. The overall objective of this work is to identify a computational metric that will help assess the right timing for surgical intervention in adults with repaired tetralogy of Fallot. This current study concerns a preliminary computational analysis of blood flow in simplified geometries of the pulmonary bifurcation. The focus lies on the effect of geometric and haemodynamic parameters on the wall shear stress patterns around the pulmonary bifurcation.

Conference

Conference31st Scottish Fluid Mechanics Meeting 2018
CountryUnited Kingdom
CityAberdeen
Period29/05/1829/05/18
Internet address

Fingerprint

Bifurcation (mathematics)
Flow simulation
Hemodynamics
Shear stress
Blood
Geometry

Keywords

  • blood flow simulations
  • tetralogy of fallot
  • congenital heart disease
  • pulmonary valve replacement

Cite this

@conference{2b05a9c4b3334a3abc180ab4012a68a6,
title = "Blood flow simulations in models of the pulmonary bifurcation to facilitate treatment of adults with congenital heart disease",
abstract = "Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart disease, for which patients require surgical intervention at a very young age. Although these patients have long survival rates, they are at risk of chronic complications and frequently require re-operations with the most common being pulmonary valve replacement (PVR). However, the decision for surgical intervention is currently based on clinical indications and the right timing for PVR remains ambiguous [1,2]. The overall objective of this work is to identify a computational metric that will help assess the right timing for surgical intervention in adults with repaired tetralogy of Fallot. This current study concerns a preliminary computational analysis of blood flow in simplified geometries of the pulmonary bifurcation. The focus lies on the effect of geometric and haemodynamic parameters on the wall shear stress patterns around the pulmonary bifurcation.",
keywords = "blood flow simulations, tetralogy of fallot, congenital heart disease, pulmonary valve replacement",
author = "M. Boumpouli and M. Danton and T. Gourlay and A. Kazakidi",
year = "2018",
month = "5",
day = "29",
language = "English",
note = "31st Scottish Fluid Mechanics Meeting 2018 ; Conference date: 29-05-2018 Through 29-05-2018",
url = "https://www.abdn.ac.uk/engineering/events/12948/",

}

Blood flow simulations in models of the pulmonary bifurcation to facilitate treatment of adults with congenital heart disease. / Boumpouli, M.; Danton, M.; Gourlay, T.; Kazakidi, A.

2018. Abstract from 31st Scottish Fluid Mechanics Meeting 2018, Aberdeen, United Kingdom.

Research output: Contribution to conferenceAbstract

TY - CONF

T1 - Blood flow simulations in models of the pulmonary bifurcation to facilitate treatment of adults with congenital heart disease

AU - Boumpouli, M.

AU - Danton, M.

AU - Gourlay, T.

AU - Kazakidi, A.

PY - 2018/5/29

Y1 - 2018/5/29

N2 - Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart disease, for which patients require surgical intervention at a very young age. Although these patients have long survival rates, they are at risk of chronic complications and frequently require re-operations with the most common being pulmonary valve replacement (PVR). However, the decision for surgical intervention is currently based on clinical indications and the right timing for PVR remains ambiguous [1,2]. The overall objective of this work is to identify a computational metric that will help assess the right timing for surgical intervention in adults with repaired tetralogy of Fallot. This current study concerns a preliminary computational analysis of blood flow in simplified geometries of the pulmonary bifurcation. The focus lies on the effect of geometric and haemodynamic parameters on the wall shear stress patterns around the pulmonary bifurcation.

AB - Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart disease, for which patients require surgical intervention at a very young age. Although these patients have long survival rates, they are at risk of chronic complications and frequently require re-operations with the most common being pulmonary valve replacement (PVR). However, the decision for surgical intervention is currently based on clinical indications and the right timing for PVR remains ambiguous [1,2]. The overall objective of this work is to identify a computational metric that will help assess the right timing for surgical intervention in adults with repaired tetralogy of Fallot. This current study concerns a preliminary computational analysis of blood flow in simplified geometries of the pulmonary bifurcation. The focus lies on the effect of geometric and haemodynamic parameters on the wall shear stress patterns around the pulmonary bifurcation.

KW - blood flow simulations

KW - tetralogy of fallot

KW - congenital heart disease

KW - pulmonary valve replacement

UR - https://www.abdn.ac.uk/engineering/events/12948/

M3 - Abstract

ER -