Projects per year
Abstract
The complex patterns observed from evaporated liquid drops have been examined extensively over the last 20 years. Complete understanding of drop deposition is vital in many medical processes, and one which is essential to the translation of biofluid spectroscopic disease diagnostics. The promising use of spectroscopy in disease diagnosis has been hindered by the complicated patterns left by dried biological fluids which may inhibit the clinical translation of this technology. Coffee ring formation, cracking and gelation patterns have all been observed in biofluid drops, and with surface homogeneity being a key element to many spectroscopic techniques, experimental issues have been found to arise. A better understanding of the fundamental processes involved in a drying droplet could allow efficient progression in this research field, and ultimately benefit the population with the development of a reliable cancer diagnostic.
Original language | English |
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Article number | e201700299 |
Number of pages | 12 |
Journal | Journal of Biophotonics |
Volume | 11 |
Issue number | 4 |
Early online date | 26 Jan 2018 |
DOIs | |
Publication status | Published - 30 Apr 2018 |
Keywords
- drying
- FTIR spectroscopy
- disease diagnosis
- coffee ring formation
- wettability
- Marangoni flow
- serum
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Dive into the research topics of 'Biofluid spectroscopic disease diagnostics: a review on the processes and spectral impact of drying'. Together they form a unique fingerprint.Projects
- 1 Finished
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EPSRC Doctoral Training Grant - DTA, University of Strathclyde
McFarlane, A.
EPSRC (Engineering and Physical Sciences Research Council)
1/10/13 → 30/09/17
Project: Research - Studentship