Biofabrication and biomanufacturing in Ireland and the UK

Jack F. Murphy, Martha Lavelle, Lisa Asciak, Ross Burdis, Hannah J. Levis, Cosimo Ligorio, Jamie McGuire, Marlene Polleres, Poppy O. Smith, Lucinda Tullie, Juan Uribe-Gomez, Biqiong Chen, Jonathan I. Dawson, Julien E. Gautrot, Nigel M. Hooper, Daniel J. Kelly, Vivian S. W. Li, Alvaro Mata, Abhay Pandit, James B. PhillipsWenmiao Shu, Molly M. Stevens, Rachel L. Williams, James P. K. Armstrong*, Yan Yan Shery Huang*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

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Abstract

As we navigate the transition from the Fourth to the Fifth Industrial Revolution, the emerging fields of biomanufacturing and biofabrication are transforming life sciences and healthcare. These sectors are benefiting from a synergy of synthetic and engineering biology, sustainable manufacturing, and integrated design principles. Advanced techniques such as 3D bioprinting, tissue engineering, directed assembly, and self-assembly are instrumental in creating biomimetic scaffolds, tissues, organoids, medical devices, and biohybrid systems. The field of biofabrication in the United Kingdom and Ireland is emerging as a pivotal force in bioscience and healthcare, propelled by cutting-edge research and development. Concentrating on the production of biologically functional products for use in drug delivery, in vitro models, and tissue engineering, research institutions across these regions are dedicated to innovating healthcare solutions that adhere to ethical standards while prioritising sustainability, affordability, and healthcare system benefits.
Original languageEnglish
Pages (from-to)825-856
Number of pages32
JournalBio-Design and Manufacturing
Volume7
Issue number6
Early online date23 Oct 2024
DOIs
Publication statusPublished - 1 Nov 2024

Keywords

  • Sustainability
  • Tissue engineering
  • Drug delivery
  • Biohybrid
  • Bioprinting
  • Biomaterials

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