Biocatalytic ATRP

Jonas Pollard; Nico Bruns

doi:10.1021/bk-2018-1284.ch019

Biocatalytic ATRP

Jonas Pollard, Nico Bruns

Pure And Applied Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

5 Citations (Scopus)

Abstract

Enzymes, their cofactors as well as enzyme mimetics can catalyze atom transfer radical polymerization (ATRP). Catalysts for this bioATRP are heme enzymes such as horseradish peroxidase, hemoglobin, and catalase, as well as the copper-containing laccases. Moreover, hemin, PEGylated hemin, heme-peptide conjugates, and single-chain polymer nanoparticles have been explored as ATRP catalysts. This chapter reviews biocatalytic ATRP as well as biocatalytically initiated RAFT polymerizations, and shows how "ATRPases" and other biologically derived catalysts are used, e.g., to tune well-controlled surface-initiated polymerizations, to confine ATRP into nanoreactors, and to prepare non-viral gene vectors or biosensors.

Original language	English
Title of host publication	Reversible Deactivation Radical Polymerization
Subtitle of host publication	Mechanisms and Synthetic Methodologies
Editors	Nicolay V. Tsarevsky, Haifeng Gao, Krzysztof Matyjaszewski, Brent S. Sumerlin
Publisher	American Chemical Society
Pages	379-393
Number of pages	15
Volume	1284
ISBN (Print)	9780841233188
DOIs	https://doi.org/10.1021/bk-2018-1284.ch019
Publication status	Published - 1 Jan 2018

Publication series

Name	ACS Symposium Series
Volume	1284
ISSN (Print)	0097-6156
ISSN (Electronic)	1947-5918

Funding

This work was supported by the Swiss National Science Foundation through the projects PP00P2_144697 and PP00P2_172927.

Keywords

enzymes
free radical reactions
living polymerization
porphyrins
atom transfer radical polymerization
enzyme mimetics
lipases

Access to Document

10.1021/bk-2018-1284.ch019

Cite this

@inbook{5a46717c19114670a4a6253ede97e5c0,

title = "Biocatalytic ATRP",

abstract = "Enzymes, their cofactors as well as enzyme mimetics can catalyze atom transfer radical polymerization (ATRP). Catalysts for this bioATRP are heme enzymes such as horseradish peroxidase, hemoglobin, and catalase, as well as the copper-containing laccases. Moreover, hemin, PEGylated hemin, heme-peptide conjugates, and single-chain polymer nanoparticles have been explored as ATRP catalysts. This chapter reviews biocatalytic ATRP as well as biocatalytically initiated RAFT polymerizations, and shows how {"}ATRPases{"} and other biologically derived catalysts are used, e.g., to tune well-controlled surface-initiated polymerizations, to confine ATRP into nanoreactors, and to prepare non-viral gene vectors or biosensors.",

keywords = "enzymes, free radical reactions, living polymerization, porphyrins, atom transfer radical polymerization, enzyme mimetics, lipases",

author = "Jonas Pollard and Nico Bruns",

year = "2018",

month = jan,

day = "1",

doi = "10.1021/bk-2018-1284.ch019",

language = "English",

isbn = "9780841233188",

volume = "1284",

series = "ACS Symposium Series",

publisher = "American Chemical Society",

pages = "379--393",

editor = "Tsarevsky, {Nicolay V.} and Haifeng Gao and Krzysztof Matyjaszewski and Sumerlin, {Brent S.}",

booktitle = "Reversible Deactivation Radical Polymerization",

address = "United States",

}

Biocatalytic ATRP. / Pollard, Jonas; Bruns, Nico.
Reversible Deactivation Radical Polymerization: Mechanisms and Synthetic Methodologies. ed. / Nicolay V. Tsarevsky; Haifeng Gao; Krzysztof Matyjaszewski; Brent S. Sumerlin. Vol. 1284 American Chemical Society, 2018. p. 379-393 (ACS Symposium Series; Vol. 1284).

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

TY - CHAP

T1 - Biocatalytic ATRP

AU - Pollard, Jonas

AU - Bruns, Nico

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Enzymes, their cofactors as well as enzyme mimetics can catalyze atom transfer radical polymerization (ATRP). Catalysts for this bioATRP are heme enzymes such as horseradish peroxidase, hemoglobin, and catalase, as well as the copper-containing laccases. Moreover, hemin, PEGylated hemin, heme-peptide conjugates, and single-chain polymer nanoparticles have been explored as ATRP catalysts. This chapter reviews biocatalytic ATRP as well as biocatalytically initiated RAFT polymerizations, and shows how "ATRPases" and other biologically derived catalysts are used, e.g., to tune well-controlled surface-initiated polymerizations, to confine ATRP into nanoreactors, and to prepare non-viral gene vectors or biosensors.

AB - Enzymes, their cofactors as well as enzyme mimetics can catalyze atom transfer radical polymerization (ATRP). Catalysts for this bioATRP are heme enzymes such as horseradish peroxidase, hemoglobin, and catalase, as well as the copper-containing laccases. Moreover, hemin, PEGylated hemin, heme-peptide conjugates, and single-chain polymer nanoparticles have been explored as ATRP catalysts. This chapter reviews biocatalytic ATRP as well as biocatalytically initiated RAFT polymerizations, and shows how "ATRPases" and other biologically derived catalysts are used, e.g., to tune well-controlled surface-initiated polymerizations, to confine ATRP into nanoreactors, and to prepare non-viral gene vectors or biosensors.

KW - enzymes

KW - free radical reactions

KW - living polymerization

KW - porphyrins

KW - atom transfer radical polymerization

KW - enzyme mimetics

KW - lipases

UR - http://www.scopus.com/inward/record.url?scp=85052812903&partnerID=8YFLogxK

U2 - 10.1021/bk-2018-1284.ch019

DO - 10.1021/bk-2018-1284.ch019

M3 - Chapter (peer-reviewed)

AN - SCOPUS:85052812903

SN - 9780841233188

VL - 1284

T3 - ACS Symposium Series

SP - 379

EP - 393

BT - Reversible Deactivation Radical Polymerization

A2 - Tsarevsky, Nicolay V.

A2 - Gao, Haifeng

A2 - Matyjaszewski, Krzysztof

A2 - Sumerlin, Brent S.

PB - American Chemical Society

ER -

Biocatalytic ATRP

Abstract

Publication series

Funding

Keywords

Access to Document

Other files and links

Fingerprint

Cite this