Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines

Ruangelie Edrada-Ebel; V Wray; L Witte; L van Ofwegen; P Proksch

Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines

Ruangelie Edrada-Ebel, V Wray, L Witte, L van Ofwegen, P Proksch

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article

29 Citations (Scopus)

Abstract

A marine soft coral species of the genus Heteroxenia collected from Mindoro Island, Philippines yielded two cadinene sesquiterpenes, (+)-alpha-muurolene (1) and a novel derivative (+)-6-hydroxy-alpha-muurolene (2), as well as the biologically active polyhydroxysterol, sarcoaldosterol A (3). The structure of the novel compound was unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H-detected direct and long range 13C-1H correlations) and mass spectrometric (EIMS) data. All compounds were active against the phytopathogenic fungus Cladosporium cucumerinum. The isolated terpenes were also active in the brine shrimp lethality test.

Original language	English
Pages (from-to)	82-86
Number of pages	5
Journal	Zeitschrift fur Naturforschung C
Volume	55
Issue number	1-2
Publication status	Published - 30 Mar 2000

Keywords

animals
artemia
cladosporium
cnidaria
magnetic resonance spectroscopy
molecular conformation
molecular structure
philippines
sesquiterpenes
spectrometry, mass, secondary ion
Terpenes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines",

abstract = "A marine soft coral species of the genus Heteroxenia collected from Mindoro Island, Philippines yielded two cadinene sesquiterpenes, (+)-alpha-muurolene (1) and a novel derivative (+)-6-hydroxy-alpha-muurolene (2), as well as the biologically active polyhydroxysterol, sarcoaldosterol A (3). The structure of the novel compound was unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H-detected direct and long range 13C-1H correlations) and mass spectrometric (EIMS) data. All compounds were active against the phytopathogenic fungus Cladosporium cucumerinum. The isolated terpenes were also active in the brine shrimp lethality test.",

keywords = "animals, artemia, cladosporium, cnidaria, magnetic resonance spectroscopy, molecular conformation, molecular structure, philippines, sesquiterpenes, spectrometry, mass, secondary ion, Terpenes",

author = "Ruangelie Edrada-Ebel and V Wray and L Witte and {van Ofwegen}, L and P Proksch",

year = "2000",

month = mar,

day = "30",

language = "English",

volume = "55",

pages = "82--86",

journal = "Zeitschrift fur Naturforschung C",

issn = "0939-5075",

publisher = "Walter de Gruyter GmbH",

number = "1-2",

}

TY - JOUR

T1 - Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines

AU - Edrada-Ebel, Ruangelie

AU - Wray, V

AU - Witte, L

AU - van Ofwegen, L

AU - Proksch, P

PY - 2000/3/30

Y1 - 2000/3/30

N2 - A marine soft coral species of the genus Heteroxenia collected from Mindoro Island, Philippines yielded two cadinene sesquiterpenes, (+)-alpha-muurolene (1) and a novel derivative (+)-6-hydroxy-alpha-muurolene (2), as well as the biologically active polyhydroxysterol, sarcoaldosterol A (3). The structure of the novel compound was unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H-detected direct and long range 13C-1H correlations) and mass spectrometric (EIMS) data. All compounds were active against the phytopathogenic fungus Cladosporium cucumerinum. The isolated terpenes were also active in the brine shrimp lethality test.

AB - A marine soft coral species of the genus Heteroxenia collected from Mindoro Island, Philippines yielded two cadinene sesquiterpenes, (+)-alpha-muurolene (1) and a novel derivative (+)-6-hydroxy-alpha-muurolene (2), as well as the biologically active polyhydroxysterol, sarcoaldosterol A (3). The structure of the novel compound was unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H-detected direct and long range 13C-1H correlations) and mass spectrometric (EIMS) data. All compounds were active against the phytopathogenic fungus Cladosporium cucumerinum. The isolated terpenes were also active in the brine shrimp lethality test.

KW - animals

KW - artemia

KW - cladosporium

KW - cnidaria

KW - magnetic resonance spectroscopy

KW - molecular conformation

KW - molecular structure

KW - philippines

KW - sesquiterpenes

KW - spectrometry, mass, secondary ion

KW - Terpenes

UR - http://www.znaturforsch.com/ac/v55c/c55c.htm

M3 - Article

C2 - 10739105

SN - 0939-5075

VL - 55

SP - 82

EP - 86

JO - Zeitschrift fur Naturforschung C

JF - Zeitschrift fur Naturforschung C

IS - 1-2

ER -

Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines

Abstract

Keywords

UN SDGs

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