Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines

Ruangelie Edrada-Ebel, V Wray, L Witte, L van Ofwegen, P Proksch

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A marine soft coral species of the genus Heteroxenia collected from Mindoro Island, Philippines yielded two cadinene sesquiterpenes, (+)-alpha-muurolene (1) and a novel derivative (+)-6-hydroxy-alpha-muurolene (2), as well as the biologically active polyhydroxysterol, sarcoaldosterol A (3). The structure of the novel compound was unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H-detected direct and long range 13C-1H correlations) and mass spectrometric (EIMS) data. All compounds were active against the phytopathogenic fungus Cladosporium cucumerinum. The isolated terpenes were also active in the brine shrimp lethality test.

LanguageEnglish
Pages82-86
Number of pages5
JournalZeitschrift fur Naturforschung C
Volume55
Issue number1-2
Publication statusPublished - 30 Mar 2000

Fingerprint

Cladosporium
Artemia
Anthozoa
Philippines
Sesquiterpenes
Terpenes
Fungi
Islands
Nuclear magnetic resonance
Derivatives
Proton Magnetic Resonance Spectroscopy
brine

Keywords

  • animals
  • artemia
  • cladosporium
  • cnidaria
  • magnetic resonance spectroscopy
  • molecular conformation
  • molecular structure
  • philippines
  • sesquiterpenes
  • spectrometry, mass, secondary ion
  • Terpenes

Cite this

Edrada-Ebel, Ruangelie ; Wray, V ; Witte, L ; van Ofwegen, L ; Proksch, P. / Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines. In: Zeitschrift fur Naturforschung C. 2000 ; Vol. 55, No. 1-2. pp. 82-86.
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Edrada-Ebel, R, Wray, V, Witte, L, van Ofwegen, L & Proksch, P 2000, 'Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines' Zeitschrift fur Naturforschung C, vol. 55, no. 1-2, pp. 82-86.

Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines. / Edrada-Ebel, Ruangelie; Wray, V; Witte, L; van Ofwegen, L; Proksch, P.

In: Zeitschrift fur Naturforschung C, Vol. 55, No. 1-2, 30.03.2000, p. 82-86.

Research output: Contribution to journalArticle

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