Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines

Ruangelie Edrada-Ebel, V Wray, L Witte, L van Ofwegen, P Proksch

Research output: Contribution to journalArticle

27 Citations (Scopus)


A marine soft coral species of the genus Heteroxenia collected from Mindoro Island, Philippines yielded two cadinene sesquiterpenes, (+)-alpha-muurolene (1) and a novel derivative (+)-6-hydroxy-alpha-muurolene (2), as well as the biologically active polyhydroxysterol, sarcoaldosterol A (3). The structure of the novel compound was unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H-detected direct and long range 13C-1H correlations) and mass spectrometric (EIMS) data. All compounds were active against the phytopathogenic fungus Cladosporium cucumerinum. The isolated terpenes were also active in the brine shrimp lethality test.

Original languageEnglish
Pages (from-to)82-86
Number of pages5
JournalZeitschrift fur Naturforschung C
Issue number1-2
Publication statusPublished - 30 Mar 2000


  • animals
  • artemia
  • cladosporium
  • cnidaria
  • magnetic resonance spectroscopy
  • molecular conformation
  • molecular structure
  • philippines
  • sesquiterpenes
  • spectrometry, mass, secondary ion
  • Terpenes


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