TY - JOUR
T1 - Bioactive calcium phosphate–based glasses and ceramics and their biomedical applications
T2 - a review
AU - Islam, Md Towhidul
AU - Felfel, Reda M
AU - Abou Neel, Ensanya A
AU - Grant, David M
AU - Ahmed, Ifty
AU - Hossain, Kazi M Zakir
PY - 2017/7/21
Y1 - 2017/7/21
N2 - An overview of the formation of calcium phosphate under in vitro environment on the surface of a range of bioactive materials (e.g. from silicate, borate, and phosphate glasses, glass-ceramics, bioceramics to metals) based on recent literature is presented in this review. The mechanism of bone-like calcium phosphate (i.e. hydroxyapatite) formation and the test protocols that are either already in use or currently being investigated for the evaluation of the bioactivity of biomaterials are discussed. This review also highlights the effect of chemical composition and surface charge of materials, types of medium (e.g. simulated body fluid, phosphate-buffered saline and cell culture medium) and test parameters on their bioactivity performance. Finally, a brief summary of the biomedical applications of these newly formed calcium phosphate (either in the form of amorphous or apatite) is presented.
AB - An overview of the formation of calcium phosphate under in vitro environment on the surface of a range of bioactive materials (e.g. from silicate, borate, and phosphate glasses, glass-ceramics, bioceramics to metals) based on recent literature is presented in this review. The mechanism of bone-like calcium phosphate (i.e. hydroxyapatite) formation and the test protocols that are either already in use or currently being investigated for the evaluation of the bioactivity of biomaterials are discussed. This review also highlights the effect of chemical composition and surface charge of materials, types of medium (e.g. simulated body fluid, phosphate-buffered saline and cell culture medium) and test parameters on their bioactivity performance. Finally, a brief summary of the biomedical applications of these newly formed calcium phosphate (either in the form of amorphous or apatite) is presented.
KW - bioactivity
KW - calcium phosphate
KW - ceramic
KW - glass
KW - In vitro
U2 - 10.1177/2041731417719170
DO - 10.1177/2041731417719170
M3 - Article
AN - SCOPUS:85057029169
VL - 8
SP - 1
EP - 16
JO - Journal of Tissue Engineering
JF - Journal of Tissue Engineering
ER -