Bactericidal effects of 405-nm light exposure demonstrated by inactivation of Escherichia, Salmonella, Shigella, Listeria and Mycobacterium species in liquid suspensions and on exposed surfaces

Lynne Murdoch, Michelle MacLean, E Endarko, Scott MacGregor, John Anderson

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62 Citations (Scopus)

Abstract

The bactericidal effect of 405 nm light was investigated on taxonomically diverse bacterial pathogens from the genera Salmonella, Shigella, Escherichia, Listeria, and Mycobacterium. High-intensity 405 nm light, generated from an array of 405-nm light-emitting diodes (LEDs), was used to inactivate bacteria in liquid suspension and on exposed surfaces. L. monocytogenes was most readily inactivated in suspension, whereas S. enterica was most resistant. In surface exposure tests, L. monocytogenes was more susceptible than Gram-negative enteric bacteria to 405 nm light when exposed on an agar surface but interestingly less susceptible than S. enterica after drying onto PVC and acrylic surfaces. The study findings, that 405 nm light inactivates diverse types of bacteria in liquids and on surfaces, in addition to the safety advantages of this visible (non-UV wavelength) light, indicate the potential of this technology for a range of decontamination applications.
LanguageEnglish
Article number137805
Number of pages8
JournalScientificWorld Journal
Volume2012
DOIs
Publication statusPublished - 2012

Fingerprint

Listeria
Escherichia
Salmonella
Shigella
Mycobacterium
Suspensions
Light
liquid
Liquids
Bacteria
bacterium
Decontamination
Pathogens
Polyvinyl Chloride
Acrylics
Agar
Light emitting diodes
Enterobacteriaceae
Gram-Negative Bacteria
Drying

Keywords

  • 405 nm light
  • Salmonella
  • Shigella
  • Escherichia
  • Listeria
  • Mycobacterium
  • decontamination applications

Cite this

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title = "Bactericidal effects of 405-nm light exposure demonstrated by inactivation of Escherichia, Salmonella, Shigella, Listeria and Mycobacterium species in liquid suspensions and on exposed surfaces",
abstract = "The bactericidal effect of 405 nm light was investigated on taxonomically diverse bacterial pathogens from the genera Salmonella, Shigella, Escherichia, Listeria, and Mycobacterium. High-intensity 405 nm light, generated from an array of 405-nm light-emitting diodes (LEDs), was used to inactivate bacteria in liquid suspension and on exposed surfaces. L. monocytogenes was most readily inactivated in suspension, whereas S. enterica was most resistant. In surface exposure tests, L. monocytogenes was more susceptible than Gram-negative enteric bacteria to 405 nm light when exposed on an agar surface but interestingly less susceptible than S. enterica after drying onto PVC and acrylic surfaces. The study findings, that 405 nm light inactivates diverse types of bacteria in liquids and on surfaces, in addition to the safety advantages of this visible (non-UV wavelength) light, indicate the potential of this technology for a range of decontamination applications.",
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T1 - Bactericidal effects of 405-nm light exposure demonstrated by inactivation of Escherichia, Salmonella, Shigella, Listeria and Mycobacterium species in liquid suspensions and on exposed surfaces

AU - Murdoch, Lynne

AU - MacLean, Michelle

AU - Endarko, E

AU - MacGregor, Scott

AU - Anderson, John

PY - 2012

Y1 - 2012

N2 - The bactericidal effect of 405 nm light was investigated on taxonomically diverse bacterial pathogens from the genera Salmonella, Shigella, Escherichia, Listeria, and Mycobacterium. High-intensity 405 nm light, generated from an array of 405-nm light-emitting diodes (LEDs), was used to inactivate bacteria in liquid suspension and on exposed surfaces. L. monocytogenes was most readily inactivated in suspension, whereas S. enterica was most resistant. In surface exposure tests, L. monocytogenes was more susceptible than Gram-negative enteric bacteria to 405 nm light when exposed on an agar surface but interestingly less susceptible than S. enterica after drying onto PVC and acrylic surfaces. The study findings, that 405 nm light inactivates diverse types of bacteria in liquids and on surfaces, in addition to the safety advantages of this visible (non-UV wavelength) light, indicate the potential of this technology for a range of decontamination applications.

AB - The bactericidal effect of 405 nm light was investigated on taxonomically diverse bacterial pathogens from the genera Salmonella, Shigella, Escherichia, Listeria, and Mycobacterium. High-intensity 405 nm light, generated from an array of 405-nm light-emitting diodes (LEDs), was used to inactivate bacteria in liquid suspension and on exposed surfaces. L. monocytogenes was most readily inactivated in suspension, whereas S. enterica was most resistant. In surface exposure tests, L. monocytogenes was more susceptible than Gram-negative enteric bacteria to 405 nm light when exposed on an agar surface but interestingly less susceptible than S. enterica after drying onto PVC and acrylic surfaces. The study findings, that 405 nm light inactivates diverse types of bacteria in liquids and on surfaces, in addition to the safety advantages of this visible (non-UV wavelength) light, indicate the potential of this technology for a range of decontamination applications.

KW - 405 nm light

KW - Salmonella

KW - Shigella

KW - Escherichia

KW - Listeria

KW - Mycobacterium

KW - decontamination applications

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