BacHBerry: BACterial hosts for production of bioactive phenolics from bERRY fruits

Alexey Dudnik, Mahdi Doostmohammadi, BacHBerry Consortium

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

BACterial Hosts for production of Bioactive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production of novel high-value phenolic compounds isolated from berry fruits using bacterial platforms. The project aimed at covering all stages of the discovery and pre-commercialization process, including berry collection, screening and characterization of their bioactive components, identification and functional characterization of the corresponding biosynthetic pathways, and construction of Gram-positive bacterial cell factories producing phenolic compounds. Further activities included optimization of polyphenol extraction methods from bacterial cultures, scale-up of production by fermentation up to pilot scale, as well as societal and economic analyses of the processes. This review article summarizes some of the key findings obtained throughout the duration of the project.

Original languageEnglish
Pages (from-to)291-326
Number of pages36
JournalPhytochemistry Reviews
Volume17
Issue number2
Early online date8 Sep 2017
DOIs
Publication statusPublished - 1 Apr 2018

Keywords

  • berries
  • bioprospecting
  • microbial cell factories
  • polyphenols
  • sustainable production

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