An assay for the presence of an analyte or determining a biological or medical parameter comprising the steps of adding an assay component to a pH-sensitive material charged with magnetic particles, wherein the assay component causes a pH change which is a function of the analyte or parameter to be measured; subjecting the magnetic particles to an oscillating magnetic field; and measuring the effect of the magnetic field on the magnetic particles. The assay is an enzyme immunoassay. A kit for practicing the enzyme immunoassay is also described.
|Patent number||United States Patent 6235491|
|Publication status||Published - 22 May 2001|
- biological parameter
- medical parameter