Assay utilizing magnetic particles

P. Connolly (Inventor)

Research output: Patent

20 Downloads (Pure)


An assay for the presence of an analyte or determining a biological or medical parameter comprising the steps of adding an assay component to a pH-sensitive material charged with magnetic particles, wherein the assay component causes a pH change which is a function of the analyte or parameter to be measured; subjecting the magnetic particles to an oscillating magnetic field; and measuring the effect of the magnetic field on the magnetic particles. The assay is an enzyme immunoassay. A kit for practicing the enzyme immunoassay is also described.
Original languageEnglish
Patent numberUnited States Patent 6235491
Publication statusPublished - 22 May 2001


  • biological parameter
  • medical parameter
  • assay


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