TY - JOUR
T1 - Araçain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw
AU - Macaúbas-Silva, Camila
AU - Félix, Maysa D. G.
AU - Aquino, Ana Karoline S. de
AU - Pereira-Júnior, Paulo G.
AU - Brito, Emmily Vieira de O.
AU - Oliveira-Filho, Abrahão A. de
AU - Igoli, John O.
AU - Watson, David G.
AU - Teles, Yanna C. F.
PY - 2021/7/18
Y1 - 2021/7/18
N2 - Psidium guineense Sw. (Myrtaceae) is a shrub distributed all over South America and Brazil. Its leaves are traditionally used to treat digestive problems and infections. Several biological activities have been reported for P. guineense extracts, however phytochemical studies are scarce. The present study is on the isolation of compounds from P. guineense leaf extracts using chromatographic and spectroscopic techniques and evaluation of their antibacterial activity. Araçain, a tyrosol derivative was isolated as a natural product for the first time. Other compounds isolated were ursolic acid, a phaeophorbide and three flavonoids. The extracts were tested for their antimicrobial activity against Klebsiella pneumoniae strains and they showed moderate to high antibacterial activity.
AB - Psidium guineense Sw. (Myrtaceae) is a shrub distributed all over South America and Brazil. Its leaves are traditionally used to treat digestive problems and infections. Several biological activities have been reported for P. guineense extracts, however phytochemical studies are scarce. The present study is on the isolation of compounds from P. guineense leaf extracts using chromatographic and spectroscopic techniques and evaluation of their antibacterial activity. Araçain, a tyrosol derivative was isolated as a natural product for the first time. Other compounds isolated were ursolic acid, a phaeophorbide and three flavonoids. The extracts were tested for their antimicrobial activity against Klebsiella pneumoniae strains and they showed moderate to high antibacterial activity.
KW - Psidium guineense Sw.
KW - araçain
KW - 2-(4-hydroxyphenyl)ethyl hexanoate
KW - Klebsiella pneumoniae
U2 - 10.1080/14786419.2019.1672683
DO - 10.1080/14786419.2019.1672683
M3 - Article
VL - 35
SP - 2424
EP - 2428
JO - Natural Product Research
JF - Natural Product Research
SN - 1478-6419
IS - 14
ER -