Araçain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw

Camila Macaúbas-Silva; Maysa D. G. Félix; Ana Karoline S. de Aquino; Paulo G. Pereira-Júnior; Emmily Vieira de O. Brito; Abrahão A. de Oliveira-Filho; John O. Igoli; David G. Watson; Yanna C. F. Teles

doi:10.1080/14786419.2019.1672683

Araçain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw

Camila Macaúbas-Silva, Maysa D. G. Félix, Ana Karoline S. de Aquino, Paulo G. Pereira-Júnior, Emmily Vieira de O. Brito, Abrahão A. de Oliveira-Filho, John O. Igoli, David G. Watson, Yanna C. F. Teles

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Psidium guineense Sw. (Myrtaceae) is a shrub distributed all over South America and Brazil. Its leaves are traditionally used to treat digestive problems and infections. Several biological activities have been reported for P. guineense extracts, however phytochemical studies are scarce. The present study is on the isolation of compounds from P. guineense leaf extracts using chromatographic and spectroscopic techniques and evaluation of their antibacterial activity. Araçain, a tyrosol derivative was isolated as a natural product for the first time. Other compounds isolated were ursolic acid, a phaeophorbide and three flavonoids. The extracts were tested for their antimicrobial activity against Klebsiella pneumoniae strains and they showed moderate to high antibacterial activity.

Original language	English
Pages (from-to)	2424-2428
Number of pages	5
Journal	Natural Product Research
Volume	35
Issue number	14
Early online date	4 Oct 2019
DOIs	https://doi.org/10.1080/14786419.2019.1672683
Publication status	Published - 18 Jul 2021

Keywords

Psidium guineense Sw.
araçain
2-(4-hydroxyphenyl)ethyl hexanoate
Klebsiella pneumoniae

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10.1080/14786419.2019.1672683

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title = "Ara{\c c}ain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw",

abstract = "Psidium guineense Sw. (Myrtaceae) is a shrub distributed all over South America and Brazil. Its leaves are traditionally used to treat digestive problems and infections. Several biological activities have been reported for P. guineense extracts, however phytochemical studies are scarce. The present study is on the isolation of compounds from P. guineense leaf extracts using chromatographic and spectroscopic techniques and evaluation of their antibacterial activity. Ara{\c c}ain, a tyrosol derivative was isolated as a natural product for the first time. Other compounds isolated were ursolic acid, a phaeophorbide and three flavonoids. The extracts were tested for their antimicrobial activity against Klebsiella pneumoniae strains and they showed moderate to high antibacterial activity.",

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T1 - Araçain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw

AU - Macaúbas-Silva, Camila

AU - Félix, Maysa D. G.

AU - Aquino, Ana Karoline S. de

AU - Pereira-Júnior, Paulo G.

AU - Brito, Emmily Vieira de O.

AU - Oliveira-Filho, Abrahão A. de

AU - Igoli, John O.

AU - Watson, David G.

AU - Teles, Yanna C. F.

PY - 2021/7/18

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N2 - Psidium guineense Sw. (Myrtaceae) is a shrub distributed all over South America and Brazil. Its leaves are traditionally used to treat digestive problems and infections. Several biological activities have been reported for P. guineense extracts, however phytochemical studies are scarce. The present study is on the isolation of compounds from P. guineense leaf extracts using chromatographic and spectroscopic techniques and evaluation of their antibacterial activity. Araçain, a tyrosol derivative was isolated as a natural product for the first time. Other compounds isolated were ursolic acid, a phaeophorbide and three flavonoids. The extracts were tested for their antimicrobial activity against Klebsiella pneumoniae strains and they showed moderate to high antibacterial activity.

AB - Psidium guineense Sw. (Myrtaceae) is a shrub distributed all over South America and Brazil. Its leaves are traditionally used to treat digestive problems and infections. Several biological activities have been reported for P. guineense extracts, however phytochemical studies are scarce. The present study is on the isolation of compounds from P. guineense leaf extracts using chromatographic and spectroscopic techniques and evaluation of their antibacterial activity. Araçain, a tyrosol derivative was isolated as a natural product for the first time. Other compounds isolated were ursolic acid, a phaeophorbide and three flavonoids. The extracts were tested for their antimicrobial activity against Klebsiella pneumoniae strains and they showed moderate to high antibacterial activity.

KW - Psidium guineense Sw.

KW - araçain

KW - 2-(4-hydroxyphenyl)ethyl hexanoate

KW - Klebsiella pneumoniae

U2 - 10.1080/14786419.2019.1672683

DO - 10.1080/14786419.2019.1672683

M3 - Article

SN - 1478-6419

VL - 35

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EP - 2428

JO - Natural Product Research

JF - Natural Product Research

IS - 14

ER -

Araçain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw

Abstract

Keywords

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