Abstract
Dendrimers are emerging as potential non-viral vectors for efficiently delivering drugs and nucleic acids to the brain and cancer cells. These polymers are highly branched, three-dimensional macromolecules with modifiable surface functionalities and available internal cavities that make them attractive as delivery systems for drug and gene delivery applications. This review highlights the recent therapeutic advances resulting from the use of dendrimers for brain targeting and cancer treatment.
| Original language | English |
|---|---|
| Pages (from-to) | 2403-2414 |
| Number of pages | 12 |
| Journal | Nanomedicine |
| Volume | 9 |
| Issue number | 15 |
| DOIs | |
| Publication status | Published - Oct 2014 |
Keywords
- dendrimers
- non-viral vectors
- brain targeting
- cancer treatments
