Applications of dendrimers for brain delivery and cancer therapy

Sukrut Somani, Christine Dufès

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Dendrimers are emerging as potential non-viral vectors for efficiently delivering drugs and nucleic acids to the brain and cancer cells. These polymers are highly branched, three-dimensional macromolecules with modifiable surface functionalities and available internal cavities that make them attractive as delivery systems for drug and gene delivery applications. This review highlights the recent therapeutic advances resulting from the use of dendrimers for brain targeting and cancer treatment.
LanguageEnglish
Pages2403-2414
Number of pages12
JournalNanomedicine
Volume9
Issue number15
DOIs
Publication statusPublished - Oct 2014

Fingerprint

Dendrimers
Gene Transfer Techniques
Drug Delivery Systems
Brain Neoplasms
brain
cancer
Brain
drug
Oncology
Nucleic acids
nucleic acid
Macromolecules
Pharmaceutical Preparations
Nucleic Acids
functionality
targeting
Polymers
cavity
polymer
Genes

Keywords

  • dendrimers
  • non-viral vectors
  • brain targeting
  • cancer treatments

Cite this

Somani, Sukrut ; Dufès, Christine. / Applications of dendrimers for brain delivery and cancer therapy. In: Nanomedicine. 2014 ; Vol. 9, No. 15. pp. 2403-2414 .
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Applications of dendrimers for brain delivery and cancer therapy. / Somani, Sukrut; Dufès, Christine.

In: Nanomedicine, Vol. 9, No. 15, 10.2014, p. 2403-2414 .

Research output: Contribution to journalArticle

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