Application of surface enhanced Raman scattering to the solution based detection of a popular legal high, 5,6-methylenedioxy-2-aminoindane (MDAI)

Samuel Mabbott, Omar Alharbi, Kate Groves, Royston Goodacre

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The ever increasing numbers and users of designer drugs means that analytical techniques have to evolve constantly to facilitate their identification and detection. We report that surface enhanced Raman scattering (SERS) offers a relatively fast and inexpensive method for the detection of MDAI at low concentrations. Careful optimisation of the silver sol, and salt concentrations was undertaken to ensure the SERS analysis was both reproducible and sensitive. The optimised system demonstrated acceptable peak variations of less than 15% RSD and resulted in a detection limit of just 8 ppm (5.4 × 10-5 M).

LanguageEnglish
Pages4399-4406
Number of pages8
JournalAnalyst
Volume140
Issue number13
Early online date5 May 2015
DOIs
Publication statusPublished - 7 Jul 2015

Fingerprint

Raman Spectrum Analysis
Raman scattering
Designer Drugs
scattering
Polymethyl Methacrylate
Sols
Silver
Limit of Detection
Salts
analytical method
silver
drug
salt
5,6-methylenedioxy-2-aminoindane
detection

Keywords

  • designer drugs
  • surface enhanced Raman scattering
  • analysis techniques

Cite this

Mabbott, Samuel ; Alharbi, Omar ; Groves, Kate ; Goodacre, Royston. / Application of surface enhanced Raman scattering to the solution based detection of a popular legal high, 5,6-methylenedioxy-2-aminoindane (MDAI). In: Analyst. 2015 ; Vol. 140, No. 13. pp. 4399-4406.
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Application of surface enhanced Raman scattering to the solution based detection of a popular legal high, 5,6-methylenedioxy-2-aminoindane (MDAI). / Mabbott, Samuel; Alharbi, Omar; Groves, Kate; Goodacre, Royston.

In: Analyst, Vol. 140, No. 13, 07.07.2015, p. 4399-4406.

Research output: Contribution to journalArticle

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