Application of molecularly imprinted polymers to solid-phase extraction of compounds from environmental and biological samples

E. Caro, R.M. Marce, F. Borrull, P.A.G. Cormack, D.C. Sherrington

Research output: Contribution to journalArticle

293 Citations (Scopus)

Abstract

In this paper, we review the current state of the art in the use of molecularly imprinted polymers (MIPs) as selective materials in molecularly imprinted solid-phase extraction (MISPE). The application of these synthetic polymers as sorbents allows not only pre-concentration and cleaning of the sample but also selective extraction of the target analyte, which is important, particularly when the sample is complex and impurities can interfere with quantification. We therefore discuss the application of MISPE to compounds from complex matrices, such as environmental and biological samples.
LanguageEnglish
Pages143-154
Number of pages11
JournalTrends in Analytical Chemistry
Volume25
Issue number2
Early online date12 Sep 2005
DOIs
Publication statusPublished - 1 Feb 2006

Fingerprint

Polymers
polymer
Sorbents
Cleaning
Impurities
matrix
state of the art
material

Keywords

  • biological sample
  • MIP
  • MISPE
  • molecularly imprinted polymer
  • molecularly imprinted solid-phase extraction
  • solid-phase extraction
  • SPE
  • water sample

Cite this

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Application of molecularly imprinted polymers to solid-phase extraction of compounds from environmental and biological samples. / Caro, E.; Marce, R.M.; Borrull, F.; Cormack, P.A.G.; Sherrington, D.C.

In: Trends in Analytical Chemistry , Vol. 25, No. 2, 01.02.2006, p. 143-154.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Application of molecularly imprinted polymers to solid-phase extraction of compounds from environmental and biological samples

AU - Caro, E.

AU - Marce, R.M.

AU - Borrull, F.

AU - Cormack, P.A.G.

AU - Sherrington, D.C.

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KW - biological sample

KW - MIP

KW - MISPE

KW - molecularly imprinted polymer

KW - molecularly imprinted solid-phase extraction

KW - solid-phase extraction

KW - SPE

KW - water sample

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