TY - JOUR
T1 - Antimicrobial utilization research and activities in Botswana, the past, present and the future
AU - Tiroyakgosi, Celda
AU - Matome, Matshediso
AU - Kgatlwane, Joyce
AU - Paramadhas, Bene D Anand
AU - Malone, Brighid
AU - Mpinda-Joseph, Pinkie
AU - Rwegerera, Godfrey Mutashambara
AU - Maika, Keamogetse
AU - Mashalla, Yohana
AU - Godman, Brian
AU - Massele, Amos
PY - 2019/10/31
Y1 - 2019/10/31
N2 - A number of activities are ongoing to reduce AMR in Botswana by improving antimicrobial utilization across all sectors. However, there is a need to share experiences. With the objective of sharing these, the second one day symposium was held in the University of Botswana in October 2018 involving both private and public hospitals. In Lenmed Bokamoso hospital, ESKAPE organisms were associated with 50-90% of clinical infections; however, there was no correlation between healthcare associated infections (HAIs) and admission swab positivity with ESKAPE or ESBL isolates. Hang times, the time between a prescription and IV administration, were also discussed. At Nyangabwe Hospital, the prevalence of HAIs was 13.54%, 48.9% were laboratory confirmed of which 8.5% were blood stream infections (BSIs). The prevalence of different bacteria causing neonatal BSIs was also investigated. At Princess Marina Hospital, positive cultures were seen in 22.4% of blood cultures with contaminants comprising the majority. Several activities are ongoing in Botswana across sectors as a result of the findings and will be periodically reported to further improve antibiotic utilization.
AB - A number of activities are ongoing to reduce AMR in Botswana by improving antimicrobial utilization across all sectors. However, there is a need to share experiences. With the objective of sharing these, the second one day symposium was held in the University of Botswana in October 2018 involving both private and public hospitals. In Lenmed Bokamoso hospital, ESKAPE organisms were associated with 50-90% of clinical infections; however, there was no correlation between healthcare associated infections (HAIs) and admission swab positivity with ESKAPE or ESBL isolates. Hang times, the time between a prescription and IV administration, were also discussed. At Nyangabwe Hospital, the prevalence of HAIs was 13.54%, 48.9% were laboratory confirmed of which 8.5% were blood stream infections (BSIs). The prevalence of different bacteria causing neonatal BSIs was also investigated. At Princess Marina Hospital, positive cultures were seen in 22.4% of blood cultures with contaminants comprising the majority. Several activities are ongoing in Botswana across sectors as a result of the findings and will be periodically reported to further improve antibiotic utilization.
KW - Botswana
KW - antimicrobials
KW - healthcare associated infections
KW - blood stream infections
KW - hang times
KW - antimicrobial resistance
KW - health policies
U2 - 10.1080/14787210.2019.1668777
DO - 10.1080/14787210.2019.1668777
M3 - Article
SN - 1478-7210
VL - 17
SP - 759
EP - 762
JO - Expert Review of Anti-infective Therapy
JF - Expert Review of Anti-infective Therapy
IS - 10
ER -