Antimicrobial point prevalence surveys in two Ghanaian hospitals: opportunities for antimicrobial stewardship

Daniel Kwame Afriyie, Israel A. Sefah, Jacqueline Sneddon, William Malcolm, Rachel McKinney, Lesley Cooper, Amanj Kurdi, Brian Godman, Andrew Seaton

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Background: There is an urgent need to support antimicrobial stewardship (AMS) and reduce antimicrobial resistance (AMR) in Ghana. Point prevalence studies (PPS) were conducted in two hospitals as part of a global health partnership project in order to: (i) provide baseline antimicrobial utilisation data for Keta Municipal Hospital (KMH) and Ghana Police Hospital (GPH) to identify priorities for improvement; (ii) assess the feasibility of conducting PPS studies; (iii) compare results with other African countries. Methods: The Global PPS system was used. Training of hospital staff was undertaken by the Scottish team prior to data collection. Results: Prevalence of antibiotic use was 65% in GPH and 82% in KMH. Penicillins and other beta-lactams were the most commonly prescribed antibiotics, with third generation cephalosporins mainly used in GPH. Antibiotics were administered empirically and usually initiated IV and infections were mainly community acquired. Indication documentation for antibiotic use in both hospitals was good and guideline compliance was > 50%. Notably for many indications no guidelines were available. Most prescriptions had recorded stop dates and there appeared to be no missed doses. Penicillin allergy was not recorded for any patients. The duration of surgical prophylaxis was generally more than one day (69% in GPH and 77% in KMH). Conclusions: PPS was feasible and achieved with limited training. Encouraging findings were seen which can be shared with other countries. Identified concerns included broad spectrum antibiotics, length of prescribing including prophylaxis and oral use post IV, and lack of freely available microbiology resources to inform treatment
Original languageEnglish
Number of pages1
Publication statusAccepted/In press - 21 Nov 2019
EventEuroDURG 2020 - Szeged, Hungary
Duration: 3 Mar 20207 Mar 2020


ConferenceEuroDURG 2020


  • Ghanaian hospitals
  • antimicrobial stewardship
  • point prevalence studies


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