Abstract
| Language | English |
|---|---|
| Patent number | US 20050142113 A1 |
| Priority date | 4/05/99 |
| Publication status | Published - 30 Jun 2005 |
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Keywords
- metabolic pathways
- Apicomplexan growth
- inhibitor
- enzymes
- vaccines
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}
Antimicrobial agents, diagnostic reagents, and vaccines based on unique apicomplexan parasite components. / McLeod, Rima (Inventor); Roberts, Craig (Inventor); Roberts, Fiona (Inventor); Johnson, Jennifer (Inventor); Kirisits, Michael (Inventor); Ferguson, David (Inventor); Lyons, Russell (Inventor); Mui, Ernest (Inventor); Mack, Doug (Inventor); Samuel, Benjamin (Inventor); Gornicki, Piotri (Inventor); Zuther, Ellen (Inventor).
Patent No.: US 20050142113 A1.Research output: Patent
TY - PAT
T1 - Antimicrobial agents, diagnostic reagents, and vaccines based on unique apicomplexan parasite components
AU - McLeod, Rima
AU - Roberts, Craig
AU - Roberts, Fiona
AU - Johnson, Jennifer
AU - Kirisits, Michael
AU - Ferguson, David
AU - Lyons, Russell
AU - Mui, Ernest
AU - Mack, Doug
AU - Samuel, Benjamin
AU - Gornicki, Piotri
AU - Zuther, Ellen
PY - 2005/6/30
Y1 - 2005/6/30
N2 - This invention relates uses of components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally operative in animals or encoded by the plastid DNA, to develop compositions that interfere with Apicomplexan growth and survival. Components of the pathways include enzymes, transit peptides and nucleotide sequences encoding the enzymes and peptides, or promoters of these nucleotide sequences to which antibodies, antisense molecules and other inhibitors are directed. Diagnostic and therapeutic reagents and vaccines are developed based on the components and their inhibitors.
AB - This invention relates uses of components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally operative in animals or encoded by the plastid DNA, to develop compositions that interfere with Apicomplexan growth and survival. Components of the pathways include enzymes, transit peptides and nucleotide sequences encoding the enzymes and peptides, or promoters of these nucleotide sequences to which antibodies, antisense molecules and other inhibitors are directed. Diagnostic and therapeutic reagents and vaccines are developed based on the components and their inhibitors.
KW - metabolic pathways
KW - Apicomplexan growth
KW - inhibitor
KW - enzymes
KW - vaccines
M3 - Patent
M1 - US 20050142113 A1
ER -