Antibiotic use in acute respiratory infections in under-fives in Uganda: findings and implications

Dan Kibuule, Rachel Hariet Kagoya, Brian Godman

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objectives: Self-medication with antibiotics among households is common in Uganda. However limited studies evaluating self-purchasing of antibiotics for acute respiratory infections (ARI) in the under-fives. Consequently, the objective was to evaluate patterns of household self-medication with antibiotics in ARI among under-fives in Kampala. Methods: Descriptive cross-sectional observational design. Care takers at households were selected from five divisions of Kampala using the WHO 30-cluster method and interviewed using a standardized questionnaire in June - July 2011. Results: Out of the 200 households, most ARI cases 107 (53.5%; p = 0.322) were inappropriately managed. The prevalence of antibiotic use in ARI was 43% (p < 0.001). Amoxicillin 31.4% and cotrimoxazole (30%) were the most self-medicated antibiotics. Antibiotics use was associated with pneumonia symptoms and access to antibiotics. Conclusions: Household use of antibiotics in ARIs among under-fives is suboptimal. There is an urgent need for guidelines on awareness to reduce self-medication of ARIs in Uganda.
LanguageEnglish
Pages1-27
Number of pages27
JournalExpert Review of Anti-infective Therapy
DOIs
Publication statusPublished - 28 Jun 2016

Fingerprint

Uganda
Respiratory Tract Infections
Anti-Bacterial Agents
Self Medication
Amoxicillin
Sulfamethoxazole Drug Combination Trimethoprim
Pneumonia
Guidelines

Keywords

  • acute respiratory infections
  • antibiotics
  • under fives
  • households
  • self medication
  • Uganda

Cite this

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title = "Antibiotic use in acute respiratory infections in under-fives in Uganda: findings and implications",
abstract = "Objectives: Self-medication with antibiotics among households is common in Uganda. However limited studies evaluating self-purchasing of antibiotics for acute respiratory infections (ARI) in the under-fives. Consequently, the objective was to evaluate patterns of household self-medication with antibiotics in ARI among under-fives in Kampala. Methods: Descriptive cross-sectional observational design. Care takers at households were selected from five divisions of Kampala using the WHO 30-cluster method and interviewed using a standardized questionnaire in June - July 2011. Results: Out of the 200 households, most ARI cases 107 (53.5{\%}; p = 0.322) were inappropriately managed. The prevalence of antibiotic use in ARI was 43{\%} (p < 0.001). Amoxicillin 31.4{\%} and cotrimoxazole (30{\%}) were the most self-medicated antibiotics. Antibiotics use was associated with pneumonia symptoms and access to antibiotics. Conclusions: Household use of antibiotics in ARIs among under-fives is suboptimal. There is an urgent need for guidelines on awareness to reduce self-medication of ARIs in Uganda.",
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Antibiotic use in acute respiratory infections in under-fives in Uganda : findings and implications. / Kibuule, Dan; Hariet Kagoya, Rachel; Godman, Brian.

In: Expert Review of Anti-infective Therapy, 28.06.2016, p. 1-27.

Research output: Contribution to journalArticle

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