Antibiotic prescribing patterns at a referral hospital in Kenya: a point prevalence survey

Lydia Momanya, Margaret Oluka, Sylvia Opanga, David Nyamu, Amanj Kurdi, Brian Godman

Research output: Contribution to conferenceAbstract

Abstract

Background: Antibiotics are important in prevention and treatment of infections and the reduction in associated morbidity and mortality. Inappropriate use can lead to antimicrobial resistance, rendering them ineffective. Studies have shown variations in antibiotic prescribing patterns across different patient populations within the same hospital. Objectives: Our study aimed at establishing the prevalence and patterns of antibiotic use in a referral hospital in Kenya, with the aim of using the data for quality improvement. Methods: A point prevalence survey was conducted at a referral hospital in Kenya in April 2017. All patients who received antibiotics were recruited from all departments. Descriptive and inferential data analysis was done to establish the patterns of antibiotic use and the associations between variables. Ethical approval was obtained from the Kenyatta National Hospital/ University of Nairobi Research and Ethics Committee. Results: A hundred and seventy nine patients were enrolled in the study. The prevalence of antibiotic prescribing was 54.7%. The highest prevalence of antibiotic prescribing was found in critical care unit and isolation ward, both at 100%. Obstetrics and gynecology department had the least prevalence at 20.8%. Penicillins (46.9%) followed by cephalosporins (44.7%) were the most prescribed antibiotic classes. A larger proportion of antibiotic prescribing was for treatment (75.4%) as compared to prophylaxis (29.0%). Majority (76.9%, n=52) of the patients on surgical prophylaxis were on prolonged duration (>1 day). Empiric prescribing accounted for 82.6% of the total antibiotic encounters while targeted treatment was recorded in 17.4%. Conclusions: The study identified several areas for potential improvement in antibiotic prescribing such as the high prevalence of inpatient antibiotic use, prolonged duration of antibiotic use in surgical prophylaxis, extensive prescribing of broad spectrum agents such as ceftriaxone and the low prevalence of targeted antibiotic prescribing.
LanguageEnglish
Number of pages1
Publication statusAccepted/In press - 25 Apr 2018
Event4th Training Workshop and Symposium MURIA Group - Windhoek, Namibia
Duration: 18 Jun 201821 Jun 2018

Conference

Conference4th Training Workshop and Symposium MURIA Group
CountryNamibia
CityWindhoek
Period18/06/1821/06/18

Fingerprint

Kenya
Referral and Consultation
Anti-Bacterial Agents
Surveys and Questionnaires
Hospital Obstetrics and Gynecology Department
Ceftriaxone
Research Ethics Committees
Cephalosporins
Critical Care
Quality Improvement
Gynecology
Penicillins
Inpatients

Keywords

  • antibiotics
  • antimicrobial resistance
  • Kenya

Cite this

Momanya, L., Oluka, M., Opanga, S., Nyamu, D., Kurdi, A., & Godman, B. (Accepted/In press). Antibiotic prescribing patterns at a referral hospital in Kenya: a point prevalence survey. Abstract from 4th Training Workshop and Symposium MURIA Group, Windhoek, Namibia.
Momanya, Lydia ; Oluka, Margaret ; Opanga, Sylvia ; Nyamu, David ; Kurdi, Amanj ; Godman, Brian. / Antibiotic prescribing patterns at a referral hospital in Kenya : a point prevalence survey. Abstract from 4th Training Workshop and Symposium MURIA Group, Windhoek, Namibia.1 p.
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abstract = "Background: Antibiotics are important in prevention and treatment of infections and the reduction in associated morbidity and mortality. Inappropriate use can lead to antimicrobial resistance, rendering them ineffective. Studies have shown variations in antibiotic prescribing patterns across different patient populations within the same hospital. Objectives: Our study aimed at establishing the prevalence and patterns of antibiotic use in a referral hospital in Kenya, with the aim of using the data for quality improvement. Methods: A point prevalence survey was conducted at a referral hospital in Kenya in April 2017. All patients who received antibiotics were recruited from all departments. Descriptive and inferential data analysis was done to establish the patterns of antibiotic use and the associations between variables. Ethical approval was obtained from the Kenyatta National Hospital/ University of Nairobi Research and Ethics Committee. Results: A hundred and seventy nine patients were enrolled in the study. The prevalence of antibiotic prescribing was 54.7{\%}. The highest prevalence of antibiotic prescribing was found in critical care unit and isolation ward, both at 100{\%}. Obstetrics and gynecology department had the least prevalence at 20.8{\%}. Penicillins (46.9{\%}) followed by cephalosporins (44.7{\%}) were the most prescribed antibiotic classes. A larger proportion of antibiotic prescribing was for treatment (75.4{\%}) as compared to prophylaxis (29.0{\%}). Majority (76.9{\%}, n=52) of the patients on surgical prophylaxis were on prolonged duration (>1 day). Empiric prescribing accounted for 82.6{\%} of the total antibiotic encounters while targeted treatment was recorded in 17.4{\%}. Conclusions: The study identified several areas for potential improvement in antibiotic prescribing such as the high prevalence of inpatient antibiotic use, prolonged duration of antibiotic use in surgical prophylaxis, extensive prescribing of broad spectrum agents such as ceftriaxone and the low prevalence of targeted antibiotic prescribing.",
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Momanya, L, Oluka, M, Opanga, S, Nyamu, D, Kurdi, A & Godman, B 2018, 'Antibiotic prescribing patterns at a referral hospital in Kenya: a point prevalence survey' 4th Training Workshop and Symposium MURIA Group, Windhoek, Namibia, 18/06/18 - 21/06/18, .

Antibiotic prescribing patterns at a referral hospital in Kenya : a point prevalence survey. / Momanya, Lydia ; Oluka, Margaret; Opanga, Sylvia; Nyamu, David ; Kurdi, Amanj; Godman, Brian.

2018. Abstract from 4th Training Workshop and Symposium MURIA Group, Windhoek, Namibia.

Research output: Contribution to conferenceAbstract

TY - CONF

T1 - Antibiotic prescribing patterns at a referral hospital in Kenya

T2 - a point prevalence survey

AU - Momanya, Lydia

AU - Oluka, Margaret

AU - Opanga, Sylvia

AU - Nyamu, David

AU - Kurdi, Amanj

AU - Godman, Brian

PY - 2018/4/25

Y1 - 2018/4/25

N2 - Background: Antibiotics are important in prevention and treatment of infections and the reduction in associated morbidity and mortality. Inappropriate use can lead to antimicrobial resistance, rendering them ineffective. Studies have shown variations in antibiotic prescribing patterns across different patient populations within the same hospital. Objectives: Our study aimed at establishing the prevalence and patterns of antibiotic use in a referral hospital in Kenya, with the aim of using the data for quality improvement. Methods: A point prevalence survey was conducted at a referral hospital in Kenya in April 2017. All patients who received antibiotics were recruited from all departments. Descriptive and inferential data analysis was done to establish the patterns of antibiotic use and the associations between variables. Ethical approval was obtained from the Kenyatta National Hospital/ University of Nairobi Research and Ethics Committee. Results: A hundred and seventy nine patients were enrolled in the study. The prevalence of antibiotic prescribing was 54.7%. The highest prevalence of antibiotic prescribing was found in critical care unit and isolation ward, both at 100%. Obstetrics and gynecology department had the least prevalence at 20.8%. Penicillins (46.9%) followed by cephalosporins (44.7%) were the most prescribed antibiotic classes. A larger proportion of antibiotic prescribing was for treatment (75.4%) as compared to prophylaxis (29.0%). Majority (76.9%, n=52) of the patients on surgical prophylaxis were on prolonged duration (>1 day). Empiric prescribing accounted for 82.6% of the total antibiotic encounters while targeted treatment was recorded in 17.4%. Conclusions: The study identified several areas for potential improvement in antibiotic prescribing such as the high prevalence of inpatient antibiotic use, prolonged duration of antibiotic use in surgical prophylaxis, extensive prescribing of broad spectrum agents such as ceftriaxone and the low prevalence of targeted antibiotic prescribing.

AB - Background: Antibiotics are important in prevention and treatment of infections and the reduction in associated morbidity and mortality. Inappropriate use can lead to antimicrobial resistance, rendering them ineffective. Studies have shown variations in antibiotic prescribing patterns across different patient populations within the same hospital. Objectives: Our study aimed at establishing the prevalence and patterns of antibiotic use in a referral hospital in Kenya, with the aim of using the data for quality improvement. Methods: A point prevalence survey was conducted at a referral hospital in Kenya in April 2017. All patients who received antibiotics were recruited from all departments. Descriptive and inferential data analysis was done to establish the patterns of antibiotic use and the associations between variables. Ethical approval was obtained from the Kenyatta National Hospital/ University of Nairobi Research and Ethics Committee. Results: A hundred and seventy nine patients were enrolled in the study. The prevalence of antibiotic prescribing was 54.7%. The highest prevalence of antibiotic prescribing was found in critical care unit and isolation ward, both at 100%. Obstetrics and gynecology department had the least prevalence at 20.8%. Penicillins (46.9%) followed by cephalosporins (44.7%) were the most prescribed antibiotic classes. A larger proportion of antibiotic prescribing was for treatment (75.4%) as compared to prophylaxis (29.0%). Majority (76.9%, n=52) of the patients on surgical prophylaxis were on prolonged duration (>1 day). Empiric prescribing accounted for 82.6% of the total antibiotic encounters while targeted treatment was recorded in 17.4%. Conclusions: The study identified several areas for potential improvement in antibiotic prescribing such as the high prevalence of inpatient antibiotic use, prolonged duration of antibiotic use in surgical prophylaxis, extensive prescribing of broad spectrum agents such as ceftriaxone and the low prevalence of targeted antibiotic prescribing.

KW - antibiotics

KW - antimicrobial resistance

KW - Kenya

UR - http://www.unam.edu.na/conferences/4th-training-workshop-and-symposium-muria-group

M3 - Abstract

ER -

Momanya L, Oluka M, Opanga S, Nyamu D, Kurdi A, Godman B. Antibiotic prescribing patterns at a referral hospital in Kenya: a point prevalence survey. 2018. Abstract from 4th Training Workshop and Symposium MURIA Group, Windhoek, Namibia.