Antagonism of the synaptic depressant actions of L-AP4 in the lateral perforant path by MAP4

T.J. Bushell, D.E. Jane, H.-W. Tse, J.C. Watkins, C.H. Davies, J. Garthwaite, G.I. Collingridge

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)

Abstract

A new mGluR antagonist, MAP4 (the α-methyl derivative of l-AP4), was found to antagonize the synaptic depressant actions of L-AP4 at the lateral perforant path synapse, in rat hippocampal slices.

Original languageEnglish
Pages (from-to)239-241
Number of pages3
JournalNeuropharmacology
Volume34
Issue number2
DOIs
Publication statusPublished - 28 Feb 1995

Keywords

  • hippocampus
  • l-AP4
  • lateral perforant path
  • Metabotropic glutamate receptor
  • mGluR4
  • synaptic transmission

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