Anion gap as a diagnostic tool to screen for elevated lactate levels in patients admitted to an acute care setting: protocol of a diagnostic test accuracy review

Stella Andrea Glasmacher, William Stones

Research output: Other contribution


To investigate whether anion gap (AG) is a sensitive and specific screening tool for elevated lactate levels. To determine whether correction of AG for albumin improves its ability to identify patients at risk of deterioration. Secondary objective: To investigate the correlation between AG and lactate as expressed by correlation coefficients. These may be pooled in a meta-analysis or summarised descriptively, depending on data availability.
Original languageEnglish
Publication statusPublished - 1 Feb 2015


  • anion gap
  • lactate levels
  • diagnostics

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