Analysing the role of ERK MAPK signalling and potential downstream cell cycle modulators in tolerance and priming of antigen-specific cd4(+) T-cells in vitro and in vivo

A.M. Morton, P. Garside, A.M. Mowat, M.M. Harnett

Research output: Contribution to journalArticle

Abstract

T-cell recognition of Ag can result in priming or tolerance depending on the context in which Ag is recognised. We have previously shown that both qualitative and quantitative differences in T-cell signalling underlie the differential outcomes of priming and tolerance of antigenspecific T-cells.
LanguageEnglish
Pages27-27
Number of pages0
JournalImmunology
Volume125
Issue numberS1
DOIs
Publication statusPublished - Dec 2008

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Cell Cycle
T-Lymphocytes
Antigens
In Vitro Techniques

Keywords

  • ERK MAPK
  • in vitro
  • in vivo
  • T-cells

Cite this

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Analysing the role of ERK MAPK signalling and potential downstream cell cycle modulators in tolerance and priming of antigen-specific cd4(+) T-cells in vitro and in vivo. / Morton, A.M.; Garside, P.; Mowat, A.M.; Harnett, M.M.

In: Immunology, Vol. 125, No. S1, 12.2008, p. 27-27.

Research output: Contribution to journalArticle

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