Analysing the role of ERK MAPK signalling and potential downstream cell cycle modulators in tolerance and priming of antigen-specific cd4(+) T-cells in vitro and in vivo

A.M. Morton; P. Garside; A.M. Mowat; M.M. Harnett

doi:10.1111/j.1365-2567.2008.02974.x

Analysing the role of ERK MAPK signalling and potential downstream cell cycle modulators in tolerance and priming of antigen-specific cd4(+) T-cells in vitro and in vivo

A.M. Morton, P. Garside, A.M. Mowat, M.M. Harnett

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

T-cell recognition of Ag can result in priming or tolerance depending on the context in which Ag is recognised. We have previously shown that both qualitative and quantitative differences in T-cell signalling underlie the differential outcomes of priming and tolerance of antigenspecific T-cells.

Original language	English
Pages (from-to)	27-27
Number of pages	0
Journal	Immunology
Volume	125
Issue number	S1
DOIs	https://doi.org/10.1111/j.1365-2567.2008.02974.x
Publication status	Published - Dec 2008

Keywords

ERK MAPK
in vitro
in vivo
T-cells

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10.1111/j.1365-2567.2008.02974.x

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title = "Analysing the role of ERK MAPK signalling and potential downstream cell cycle modulators in tolerance and priming of antigen-specific cd4(+) T-cells in vitro and in vivo",

abstract = "T-cell recognition of Ag can result in priming or tolerance depending on the context in which Ag is recognised. We have previously shown that both qualitative and quantitative differences in T-cell signalling underlie the differential outcomes of priming and tolerance of antigenspecific T-cells.",

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author = "A.M. Morton and P. Garside and A.M. Mowat and M.M. Harnett",

year = "2008",

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AU - Morton, A.M.

AU - Garside, P.

AU - Mowat, A.M.

AU - Harnett, M.M.

PY - 2008/12

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N2 - T-cell recognition of Ag can result in priming or tolerance depending on the context in which Ag is recognised. We have previously shown that both qualitative and quantitative differences in T-cell signalling underlie the differential outcomes of priming and tolerance of antigenspecific T-cells.

AB - T-cell recognition of Ag can result in priming or tolerance depending on the context in which Ag is recognised. We have previously shown that both qualitative and quantitative differences in T-cell signalling underlie the differential outcomes of priming and tolerance of antigenspecific T-cells.

KW - ERK MAPK

KW - in vitro

KW - in vivo

KW - T-cells

UR - http://dx.doi.org/10.1111/j.1365-2567.2008.02974.x

U2 - 10.1111/j.1365-2567.2008.02974.x

DO - 10.1111/j.1365-2567.2008.02974.x

M3 - Article

VL - 125

SP - 27

EP - 27

JO - Immunology

JF - Immunology

SN - 0019-2805

IS - S1

ER -

Analysing the role of ERK MAPK signalling and potential downstream cell cycle modulators in tolerance and priming of antigen-specific cd4(+) T-cells in vitro and in vivo

Abstract

Keywords

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