An oligofluorene truxene based distributed feedback laser for biosensing applications

Anne-Marie Haughey, Benoit Guilhabert, Alexander L Kanibolotsky, Peter J Skabara, Martin D Dawson, Glenn A Burley, Nicolas Laurand

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The first example of an all-organic oligofluorene truxene based distributed feedback laser for the detection of a specific protein–small molecule interaction is reported. The protein avidin was detected down to View the MathML source1μgmL−1 using our biotin-labelled biosensor platform. This interaction was both selective and reversible when biotin was replaced with desthiobiotin. Avidin detection was not perturbed by Bovine Serum Albumin up to View the MathML source50,000μgmL−1. Our biosensor offers a new detection platform that is both highly sensitive, modular and potentially re-usable.
LanguageEnglish
Pages679-686
Number of pages8
JournalBiosensors and Bioelectronics
Volume54
Early online date25 Nov 2013
DOIs
Publication statusPublished - 15 Apr 2014

Fingerprint

Avidin
Distributed feedback lasers
Biosensing Techniques
Biotin
Biosensors
Lasers
Proteins
Bovine Serum Albumin
Molecules
desthiobiotin

Keywords

  • biosensors
  • lasers
  • oligofluorene truxene

Cite this

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An oligofluorene truxene based distributed feedback laser for biosensing applications. / Haughey, Anne-Marie; Guilhabert, Benoit; Kanibolotsky, Alexander L; Skabara, Peter J; Dawson, Martin D; Burley, Glenn A; Laurand, Nicolas.

In: Biosensors and Bioelectronics, Vol. 54, 15.04.2014, p. 679-686.

Research output: Contribution to journalArticle

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