An oligofluorene truxene based distributed feedback laser for biosensing applications

Anne-Marie Haughey, Benoit Guilhabert, Alexander L Kanibolotsky, Peter J Skabara, Martin D Dawson, Glenn A Burley, Nicolas Laurand

Research output: Contribution to journalArticle

25 Citations (Scopus)
288 Downloads (Pure)

Abstract

The first example of an all-organic oligofluorene truxene based distributed feedback laser for the detection of a specific protein–small molecule interaction is reported. The protein avidin was detected down to View the MathML source1μgmL−1 using our biotin-labelled biosensor platform. This interaction was both selective and reversible when biotin was replaced with desthiobiotin. Avidin detection was not perturbed by Bovine Serum Albumin up to View the MathML source50,000μgmL−1. Our biosensor offers a new detection platform that is both highly sensitive, modular and potentially re-usable.
Original languageEnglish
Pages (from-to)679-686
Number of pages8
JournalBiosensors and Bioelectronics
Volume54
Early online date25 Nov 2013
DOIs
Publication statusPublished - 15 Apr 2014

Keywords

  • biosensors
  • lasers
  • oligofluorene truxene

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