An investigation into the compatibility of 5 potential binders for the production of artificial bone scaffolds

April Dunham; Xiu Yan; Mary Grant

An investigation into the compatibility of 5 potential binders for the production of artificial bone scaffolds

Design, Manufacturing And Engineering Management

Research output: Contribution to conference › Abstract › peer-review

Abstract

Current practice of facial reconstruction is often below patients’ expectations. This could be improved by the use of 3D printed personalised bone scaffolds. In this study the biocompatibility of 5 potential binders for this process was investigated in vitro. None of the binders showed an overt toxic effect. However, all potential
binders except for sodium trisilicate solution showed a cytostatic effect at concentrations of 100µM suggesting their use could result in an inhibitory affect on wound healing in vivo.

Original language	English
Pages	26
Number of pages	1
Publication status	Published - 2011
Event	British Toxicology Society Meeting - Nottingham, United Kingdom Duration: 5 Sept 2011 → 6 Sept 2011

Conference

Conference	British Toxicology Society Meeting
Country/Territory	United Kingdom
City	Nottingham
Period	5/09/11 → 6/09/11

Keywords

artificial bone scaffolds
bioengineering
facial reconstruction

Cite this

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title = "An investigation into the compatibility of 5 potential binders for the production of artificial bone scaffolds",

abstract = "Current practice of facial reconstruction is often below patients{\textquoteright} expectations. This could be improved by the use of 3D printed personalised bone scaffolds. In this study the biocompatibility of 5 potential binders for this process was investigated in vitro. None of the binders showed an overt toxic effect. However, all potential binders except for sodium trisilicate solution showed a cytostatic effect at concentrations of 100µM suggesting their use could result in an inhibitory affect on wound healing in vivo.",

keywords = "artificial bone scaffolds , bioengineering, facial reconstruction",

author = "April Dunham and Xiu Yan and Mary Grant",

year = "2011",

language = "English",

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note = "British Toxicology Society Meeting ; Conference date: 05-09-2011 Through 06-09-2011",

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TY - CONF

T1 - An investigation into the compatibility of 5 potential binders for the production of artificial bone scaffolds

AU - Dunham, April

AU - Yan, Xiu

AU - Grant, Mary

PY - 2011

Y1 - 2011

N2 - Current practice of facial reconstruction is often below patients’ expectations. This could be improved by the use of 3D printed personalised bone scaffolds. In this study the biocompatibility of 5 potential binders for this process was investigated in vitro. None of the binders showed an overt toxic effect. However, all potential binders except for sodium trisilicate solution showed a cytostatic effect at concentrations of 100µM suggesting their use could result in an inhibitory affect on wound healing in vivo.

AB - Current practice of facial reconstruction is often below patients’ expectations. This could be improved by the use of 3D printed personalised bone scaffolds. In this study the biocompatibility of 5 potential binders for this process was investigated in vitro. None of the binders showed an overt toxic effect. However, all potential binders except for sodium trisilicate solution showed a cytostatic effect at concentrations of 100µM suggesting their use could result in an inhibitory affect on wound healing in vivo.

KW - artificial bone scaffolds

KW - bioengineering

KW - facial reconstruction

UR - http://www.pgbiomed2011.com/session22.html

UR - http://www.robots.ox.ac.uk/~davidc/pubs/pgbiomed_proc2011.pdf

M3 - Abstract

SP - 26

T2 - British Toxicology Society Meeting

Y2 - 5 September 2011 through 6 September 2011

ER -

An investigation into the compatibility of 5 potential binders for the production of artificial bone scaffolds

Abstract

Conference

Keywords

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