An introduction to the special issue "The contribution of pannexin-1, connexins and CALHM ATP-release channels to purinergic signalling"

Research output: Contribution to journalEditorial

Abstract

As the readership of this journal understands, extracellular nucleotides, such as ATP, act via P2X and P2Y receptors to elicit many physiological and pathophysiological actions and roles throughout the body. A variety of mechanisms have been discovered and characterised by which cells can release intracellular nucleotides. This special issue of Purinergic Signalling — "The contribution of pannexin-1, connexins and CALHM ATP-release channels to purinergic signalling", assembled by myself and Nick Dale, focusses on large pore, transmembrane channels that are permeable to ATP and so enable it to act as an autocrine and paracrine signalling molecule.
Original languageEnglish
Article number519
Number of pages1
JournalPurinergic Signalling
Volume17
Issue number4
Early online date13 Nov 2021
DOIs
Publication statusPublished - 31 Dec 2021

Keywords

  • purinergic signalling
  • cell type
  • pathologies

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